Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, alpha (NFKBIA) (N-Term) Peptide
NFKBIA
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all NFKBIA products
- NFKBIA (Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, alpha (NFKBIA))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- MFQAAERPQE WAMEGPRDGL KKERLLDDRH DSGLDSMKDE EYEQMVKELQ
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-IKBA Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- NFKBIA (Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, alpha (NFKBIA))
- Synonyms
- IKBA Peptide, MAD-3 Peptide, NFKBI Peptide, AI462015 Peptide, Nfkbi Peptide, RL/IF-1 Peptide, ECI-6/IKBA Peptide, NFKBIA Peptide, ikbaB Peptide, wu:fb81f08 Peptide, zgc:56666 Peptide, zgc:77616 Peptide, ikbaA Peptide, wu:fj16a07 Peptide, zgc:85769 Peptide, NFKB inhibitor alpha Peptide, nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha Peptide, nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha b Peptide, nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha a Peptide, NFKBIA Peptide, Nfkbia Peptide, nfkbiab Peptide, nfkbiaa Peptide
- Background
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This gene encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T-cell immunodeficiency autosomal dominant disease.
Alias Symbols: IKBA, MAD-3, NFKBI
Protein Size: 317 - Molecular Weight
- 35 kDa
- Gene ID
- 4792
- NCBI Accession
- NM_020529, NP_065390
- UniProt
- P25963
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