Inducible T-Cell Co-Stimulator Ligand (ICOSLG) (N-Term) Peptide
ICOSLG
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all ICOSLG products
- ICOSLG (Inducible T-Cell Co-Stimulator Ligand (ICOSLG))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- VDSRYRNRAL MSPAGMLRGD FSLRLFNVTP QDEQKFHCLV LSQSLGFQEV
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-ICOSLG Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- ICOSLG (Inducible T-Cell Co-Stimulator Ligand (ICOSLG))
- Synonyms
- ICOSLG Peptide, AU044799 Peptide, B7-H2 Peptide, B7RP-1 Peptide, B7h Peptide, BG071784 Peptide, GI50 Peptide, GL50 Peptide, GL50-B Peptide, ICOS-L Peptide, Icoslg Peptide, LICOS Peptide, Ly115l Peptide, mKIAA0653 Peptide, B7H2 Peptide, B7RP1 Peptide, CD275 Peptide, ICOSL Peptide, Icosl Peptide, RGD1562791 Peptide, inducible T-cell costimulator ligand Peptide, icos ligand Peptide, inducible T-cell co-stimulator ligand Peptide, ICOSLG Peptide, Icosl Peptide, Icoslg Peptide
- Background
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ICOSLG is a ligand for the T-cell-specific cell surface receptor ICOS. ICOSLG acts as a costimulatory signal for T-cell proliferation and cytokine secretion, induces also B-cell proliferation and differentiation into plasma cells. ICOSLG could play an important role in mediating local tissue responses to inflammatory conditions, as well as in modulating the secondary immune response by co-stimulating memory T-cell function.
Alias Symbols: B7-H2, B7H2, B7RP-1, B7RP1, CD275, GL50, ICOS-L, ICOSL, KIAA0653, LICOS
Protein Size: 302 - Molecular Weight
- 33 kDa
- Gene ID
- 23308
- NCBI Accession
- NM_015259, NP_056074
- UniProt
- O75144
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