Tumor Necrosis Factor Receptor Superfamily, Member 14 (TNFRSF14) (Middle Region) Peptide
TNFRSF14
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all HVEM (TNFRSF14) products
- HVEM (TNFRSF14) (Tumor Necrosis Factor Receptor Superfamily, Member 14 (TNFRSF14))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- VCGCSPGHFC IVQDGDHCAA CRAYATSSPG QRVQKGGTES QDTLCQNCPP
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-TNFRSF14 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- HVEM (TNFRSF14) (Tumor Necrosis Factor Receptor Superfamily, Member 14 (TNFRSF14))
- Synonyms
- ATAR Peptide, CD270 Peptide, HVEA Peptide, HVEM Peptide, LIGHTR Peptide, TR2 Peptide, Atar Peptide, HveA Peptide, Hvem Peptide, Tnfrs14 Peptide, TNF receptor superfamily member 14 Peptide, tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator) Peptide, Tnfrsf14 Peptide, TNFRSF14 Peptide
- Target Type
- Viral Protein
- Background
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The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor was identified as a cellular mediator of herpes simplex virus (HSV) entry. Binding of HSV viral envelope glycoprotein D (gD) to this receptor protein has been shown to be part of the viral entry mechanism. The cytoplasmic region of this receptor was found to bind to several TRAF family members, which may mediate the signal transduction pathways that activate the immune response.
Alias Symbols: ATAR, HVEA, HVEM, LIGHTR, TR2, CD270
Protein Interaction Partner: BTLA,CHD3,ESR1,HDAC3,HDAC4,LTA,NRIP1,TNFRSF14,TNFSF13,TNFSF14,TRAF1,TRAF2,TRAF3,TRAF5,VIM,CHD3,GCN1L1,P4HB,PDIA6,SEC11A,TNFSF13,TNFSF14,TRAF1,TRAF2,TRAF3,TRAF5,UGGT1,VIM
Protein Size: 283 - Molecular Weight
- 31 kDa
- Gene ID
- 8764
- NCBI Accession
- NM_003820, NP_003811
- UniProt
- Q92956
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