Transcription Factor 3 (E2A Immunoglobulin Enhancer Binding Factors E12/E47) (TCF3) (N-Term) Peptide
TCF3
Reactivity: Human
Host: Synthetic
BP, WB
-
- Target See all TCF3 products
- TCF3 (Transcription Factor 3 (E2A Immunoglobulin Enhancer Binding Factors E12/E47) (TCF3))
- Protein Region
- N-Term
- Origin
- Human
-
Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- EDRPSSGSWG SGDQSSSSFD PSRTFSEGTH FTESHSSLSS STFLGPGLGG
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-TCF3 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
-
-
- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeat freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
- Target
- TCF3 (Transcription Factor 3 (E2A Immunoglobulin Enhancer Binding Factors E12/E47) (TCF3))
- Synonyms
- E2A Peptide, E47 Peptide, ITF1 Peptide, TCF-3 Peptide, VDIR Peptide, bHLHb21 Peptide, tcf3a Peptide, zgc:113045 Peptide, A1 Peptide, AA408400 Peptide, ALF2 Peptide, AW209082 Peptide, E12 Peptide, E12/E47 Peptide, ME2 Peptide, Pan1 Peptide, Pan2 Peptide, Tcfe2a Peptide, bhlhb21 Peptide, e2a Peptide, itf1 Peptide, tcfe2a Peptide, vdir Peptide, xtcf-3 Peptide, xtcf3 Peptide, G12 Peptide, TCF7L1 Peptide, XE3 Peptide, transcription factor 3 Peptide, transcription factor 3b Peptide, transcription factor 3 L homeolog Peptide, transcription factor E2a Peptide, TCF3 Peptide, tcf3b Peptide, Tcf3 Peptide, tcf3.L Peptide, tcfe2a Peptide
- Background
-
TCF3 is a transcriptional regulator. It is involved in the initiation of neuronal differentiation. Heterodimers between TCF3 and tissue-specific basic helix-loop-helix (bHLH) proteins play major roles in determining tissue-specific cell fate during embryogenesis, like muscle or early B-cell differentiation. Dimers bind DNA on E-box motifs: 5'-CANNTG-3'. TCF3 binds to the kappa-E2 site in the kappa immunoglobulin gene enhancer. It binds to IEB1 and IEB2, which are short DNA sequences in the insulin gene transcription control region.
Alias Symbols: E2A, E47, ITF1, TCF-3, VDIR, bHLHb21
Protein Size: 654 - Molecular Weight
- 71 kDa
- Gene ID
- 6929
- NCBI Accession
- NM_003200, NP_003191
- UniProt
- P15923
-
You are here:
