Transcription Factor 3 (E2A Immunoglobulin Enhancer Binding Factors E12/E47) (TCF3) Peptide
TCF3
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all TCF3 products
- TCF3 (Transcription Factor 3 (E2A Immunoglobulin Enhancer Binding Factors E12/E47) (TCF3))
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-TCF3 antibody (Catalog #: ARP38267_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- TCF3 (Transcription Factor 3 (E2A Immunoglobulin Enhancer Binding Factors E12/E47) (TCF3))
- Synonyms
- E2A Peptide, E47 Peptide, ITF1 Peptide, TCF-3 Peptide, VDIR Peptide, bHLHb21 Peptide, tcf3a Peptide, zgc:113045 Peptide, A1 Peptide, AA408400 Peptide, ALF2 Peptide, AW209082 Peptide, E12 Peptide, E12/E47 Peptide, ME2 Peptide, Pan1 Peptide, Pan2 Peptide, Tcfe2a Peptide, bhlhb21 Peptide, e2a Peptide, itf1 Peptide, tcfe2a Peptide, vdir Peptide, xtcf-3 Peptide, xtcf3 Peptide, G12 Peptide, TCF7L1 Peptide, XE3 Peptide, transcription factor 3 Peptide, transcription factor 3b Peptide, transcription factor 3 L homeolog Peptide, transcription factor E2a Peptide, TCF3 Peptide, tcf3b Peptide, Tcf3 Peptide, tcf3.L Peptide, tcfe2a Peptide
- Background
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TCF3 contains 1 basic helix-loop-helix (bHLH) domain. Heterodimers between TCF3 and tissue-specific basic helix-loop-helix (bHLH) proteins play major roles in determining tissue-specific cell fate during embryogenesis, like muscle or early B-cell differentiation. Dimers bind DNA on E-box motifs: 5'-CANNTG-3'. TCF3 binds to the kappa-E2 site in the kappa immunoglobulin gene enhancer.
Alias Symbols: E2A, E47, ITF1, VDIR, TCF-3, bHLHb21
Protein Interaction Partner: RUNX1T1,AEBP1,ASCL3,BHLHA15,CALM1,CALM3,CREBBP,CTNNB1,ELK3,EP300,FERD3L,HAND1,HAND2,HOXA1,ID1,ID2,ID3,KAT2B,LMX1B,LYL1,MAPK1,MAPK3,MAPKAPK2,MAPKAPK3,MDFI,MSC,MYF5,MYOD1,MYOG,NEDD9,PDX1,PSMD4,PSMD9,RALGAPA1,RUNX1T1,SKP2,SRF,TAL1,TAL2,TCF12,TCF21,TCF3,TFPT,TWIST1,UBE2I,CALM1,CBFA2T3,CREBBP,ELK3,EP300,HAND2,ID1,ID2,ID3,KAT2B,LDB1,LMX1A,LYL1,MAPKAPK3,MYF5,MYF6,MYOD1,MYOG,NHLH1,SKP2,TAL1,TCF3,TWIST1,UBE2I
Protein Size: 654 - Molecular Weight
- 68 kDa
- Gene ID
- 6929
- NCBI Accession
- NM_003200, NP_003191
- UniProt
- P15923
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