gamma-aminobutyric Acid (GABA) A Receptor, beta 3 (GABRB3) (Middle Region) Peptide
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- Target See all GABRB3 products
- GABRB3 (gamma-aminobutyric Acid (GABA) A Receptor, beta 3 (GABRB3))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- FYWRGGDKAV TGVERIELPQ FSIVEHRLVS RNVVFATGAY PRLSLSFRLK
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-GABRB3 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeat freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- GABRB3 (gamma-aminobutyric Acid (GABA) A Receptor, beta 3 (GABRB3))
- Synonyms
- GABRB3 Peptide, eca5 Peptide, LOC100230475 Peptide, ECA5 Peptide, A230092K12Rik Peptide, AW049585 Peptide, Cp1 Peptide, Gabrb-3 Peptide, beta3 Peptide, gamma-aminobutyric acid type A receptor beta3 subunit Peptide, gamma-aminobutyric acid (GABA) A receptor, beta 3 Peptide, gamma-aminobutyric acid type A receptor beta 3 subunit Peptide, gamma-aminobutyric acid (GABA) A receptor, subunit beta 3 Peptide, GABRB3 Peptide, gabrb3 Peptide, Gabrb3 Peptide
- Background
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This gene encodes a member of the ligand-gated ionic channel family. The encoded protein is one the subunits of a multi-subunit chloride channel that serves as the receptor for gamma-aminobutyric acid, a major inhibitory neurotransmitter of the mammalian nervous system. This gene is located on the long arm of chromosome 15 in a cluster with two other genes encoding related subunits of the family. This gene may be associated with the pathogenesis of several disorders including Angelman syndrome, Prader-Willi syndrome, nonsyndromic orofacial clefts, epilepsy and autism. Alternatively spliced transcript variants encoding distinct isoforms have been described.
Alias Symbols: GABRB3
Protein Size: 473 - Molecular Weight
- 52 kDa
- Gene ID
- 2562
- NCBI Accession
- NM_021912, NP_068712
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