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gamma-aminobutyric Acid (GABA) A Receptor, beta 3 (GABRB3) (Middle Region) Peptide

GABRB3 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN2183736
  • Target See all GABRB3 products
    GABRB3 (gamma-aminobutyric Acid (GABA) A Receptor, beta 3 (GABRB3))
    Protein Region
    Middle Region
    Origin
    Human
    Source
    • 6
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Sequence
    FYWRGGDKAV TGVERIELPQ FSIVEHRLVS RNVVFATGAY PRLSLSFRLK
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-GABRB3 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeat freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    GABRB3 (gamma-aminobutyric Acid (GABA) A Receptor, beta 3 (GABRB3))
    Synonyms
    GABRB3 Peptide, eca5 Peptide, LOC100230475 Peptide, ECA5 Peptide, A230092K12Rik Peptide, AW049585 Peptide, Cp1 Peptide, Gabrb-3 Peptide, beta3 Peptide, gamma-aminobutyric acid type A receptor beta3 subunit Peptide, gamma-aminobutyric acid (GABA) A receptor, beta 3 Peptide, gamma-aminobutyric acid type A receptor beta 3 subunit Peptide, gamma-aminobutyric acid (GABA) A receptor, subunit beta 3 Peptide, GABRB3 Peptide, gabrb3 Peptide, Gabrb3 Peptide
    Background
    This gene encodes a member of the ligand-gated ionic channel family. The encoded protein is one the subunits of a multi-subunit chloride channel that serves as the receptor for gamma-aminobutyric acid, a major inhibitory neurotransmitter of the mammalian nervous system. This gene is located on the long arm of chromosome 15 in a cluster with two other genes encoding related subunits of the family. This gene may be associated with the pathogenesis of several disorders including Angelman syndrome, Prader-Willi syndrome, nonsyndromic orofacial clefts, epilepsy and autism. Alternatively spliced transcript variants encoding distinct isoforms have been described.

    Alias Symbols: GABRB3

    Protein Size: 473
    Molecular Weight
    52 kDa
    Gene ID
    2562
    NCBI Accession
    NM_021912, NP_068712
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