Activating Transcription Factor 7 (AFT7) (Middle Region) Peptide
AFT7
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all AFT7 products
- AFT7 (Activating Transcription Factor 7 (AFT7))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- GYDPLHPTLP SPTSVITQAP PSNRQMGSPT GSLPLVMHLA NGQTMPVLPG
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-ATF7 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Activating Transcription Factor 7 (AFT7) peptide
AFT7 Reactivity: Human, Rat, Cow, Dog Host: Synthetic BP, Imm
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- AFT7 (Activating Transcription Factor 7 (AFT7))
- Synonyms
- ATFA Peptide, 1110012F10Rik Peptide, 9430065F09Rik Peptide, AI549878 Peptide, C130020M04Rik Peptide, ATF7 Peptide, fa97a09 Peptide, fc25b12 Peptide, wu:fa97a09 Peptide, wu:fc25b12 Peptide, atfa Peptide, activating transcription factor 7 Peptide, activating transcription factor 7b Peptide, ATF7 Peptide, Atf7 Peptide, atf7b Peptide, atf7 Peptide
- Background
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Isoform 5/ATF-4 acts as a negative regulator, inhibiting both ATF2 and ATF7 transcriptional activities. It may exert these effects by sequestrating in the cytoplasm the Thr-53 phosphorylating kinase, preventing activation. FUNCTION: Isoform 4/ATF-A0 acts as a dominant repressor of the E- selectin/NF-ELAM1/delta-A promoter.ATF7 Plays important functions in early cell signaling. Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AG][AG]- 3'), a sequence present in many viral and cellular promoters. Activator of the NF-ELAM1/delta-A site of the E-selectin promoter. Has no intrinsic transcriptional activity, but activates transcription on formation of JUN or FOS heterodimers. Also can bind TRE promoter sequences when heterodimerized with members of the JUN family.
Alias Symbols: ATF7,ATFA,
Protein Size: 473 - Gene ID
- 11016
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