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Calpain, Small Subunit 1 (CAPNS1) (Middle Region) Peptide

CAPNS1 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN5511097
  • Target See all Calpain S1 (CAPNS1) products
    Calpain S1 (CAPNS1) (Calpain, Small Subunit 1 (CAPNS1))
    Protein Region
    Middle Region
    Origin
    Human
    Source
    • 3
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Sequence
    GGGGGGGGGG GGGGGGGTAM RILGGVISAI SEAAAQYNPE PPPPRTHYSN
    Characteristics
    This is a synthetic peptide designed for use in combination with anti- CAPNS1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    Calpain S1 (CAPNS1) (Calpain, Small Subunit 1 (CAPNS1))
    Synonyms
    30K Peptide, CALPAIN4 Peptide, CANP Peptide, CANPS Peptide, CAPN4 Peptide, CDPS Peptide, CSS1 Peptide, Capn4 Peptide, CAPNS1 Peptide, Capa-4 Peptide, Capa4 Peptide, D7Ertd146e Peptide, MGC84330 Peptide, capns1 Peptide, cb616 Peptide, wu:fb81g08 Peptide, wu:fl09e04 Peptide, zgc:110603 Peptide, calpain small subunit 1 Peptide, calpain, small subunit 1 Peptide, calpain, small subunit 1 L homeolog Peptide, calpain, small subunit 1 a Peptide, CAPNS1 Peptide, Capns1 Peptide, capns1.L Peptide, capns1a Peptide
    Background
    This gene is a member of the calpain small subunit family. Calpains are calcium-dependent cysteine proteinases that are widely distributed in mammalian cells. Calpains operate as heterodimers, comprising a specific large catalytic subunit (calpain 1 subunit in Calpain I, and calpain 2 subunit in Calpain II), and a common small regulatory subunit encoded by this gene. This encoded protein is essential for the stability and function of both calpain heterodimers, whose proteolytic activities influence various cellular functions including apoptosis, proliferation, migration, adhesion, and autophagy. Calpains have been implicated in neurodegenerative processes, such as myotonic dystrophy. A pseudogene of this gene has been defined on chromosome 1. Alternative splicing results in multiple transcript variants.

    Alias Symbols: CANP, CDPS, CSS1, CANPS, CAPN4, CALPAIN4

    Protein Size: 268
    Gene ID
    826
    NCBI Accession
    NM_001003962, NP_001003962
    UniProt
    P04632
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