Runt-Related Transcription Factor 3 (RUNX3) (C-Term) Peptide
RUNX3
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all RUNX3 products
- RUNX3 (Runt-Related Transcription Factor 3 (RUNX3))
- Protein Region
- C-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- PQNQSGPFQA NPSPYHLYYG TSSGSYQFSM VAGSSSGGDR SPTRMLASCT
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-RUNX3 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- RUNX3 (Runt-Related Transcription Factor 3 (RUNX3))
- Synonyms
- runxb Peptide, RUNX3 Peptide, CBFA3 Peptide, frrunx3 Peptide, runx3 Peptide, aml2 Peptide, cbfa3 Peptide, pebp2ac Peptide, AML2 Peptide, Cbfa3 Peptide, Pebp2a3 Peptide, PEBP2aC Peptide, runt-related transcription factor 3 Peptide, runt related transcription factor 3 Peptide, runt related transcription factor 3 L homeolog Peptide, runx3 Peptide, RUNX3 Peptide, runx3.L Peptide, Runx3 Peptide
- Background
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This gene encodes a member of the runt domain-containing family of transcription factors. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer. Multiple transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: RUNX3,AML2, CBFA3, PEBP2A3,
Protein Size: 415 - Gene ID
- 864
- UniProt
- Q13761
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