thromboxane A Synthase 1 (Platelet) (TBXAS1) (Middle Region) Peptide
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- Target See all TBXAS1 products
- TBXAS1 (thromboxane A Synthase 1 (Platelet) (TBXAS1))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- DPEHWPSPET FNPERFTAEA RQQHRPFTYL PFGAGPRSCL GVRLGLLEVK
- Characteristics
- This is a synthetic peptide designed for use in combination with anti- TBXAS1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- TBXAS1 (thromboxane A Synthase 1 (Platelet) (TBXAS1))
- Synonyms
- thas Peptide, TBXAS1 Peptide, wu:fk19d08 Peptide, zgc:136708 Peptide, BDPLT14 Peptide, CYP5 Peptide, CYP5A1 Peptide, GHOSAL Peptide, THAS Peptide, TS Peptide, TXAS Peptide, TXS Peptide, thromboxane-A synthase Peptide, Thromboxane-A synthase Peptide, thromboxane A synthase 1 Peptide, thromboxane A synthase 1 (platelet) Peptide, thromboxane A synthase 1, platelet Peptide, PTRG_00454 Peptide, PTRG_06796 Peptide, thas Peptide, TBXAS1 Peptide, tbxas1 Peptide, Tbxas1 Peptide
- Background
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This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. However, this protein is considered a member of the cytochrome P450 superfamily on the basis of sequence similarity rather than functional similarity. This endoplasmic reticulum membrane protein catalyzes the conversion of prostglandin H2 to thromboxane A2, a potent vasoconstrictor and inducer of platelet aggregation. The enzyme plays a role in several pathophysiological processes including hemostasis, cardiovascular disease, and stroke. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: TS, TXS, CYP5, THAS, TXAS, CYP5A1, GHOSAL, BDPLT14
Protein Size: 466 - Gene ID
- 6916
- NCBI Accession
- NM_001061, NP_001052
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