phosphodiesterase 4A, CAMP-Specific (PDE4A) (N-Term) Peptide
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- Target See all PDE4A products
- PDE4A (phosphodiesterase 4A, CAMP-Specific (PDE4A))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- FHGTGTGSGG AGGGSSRRFE AENGPTPSPG RSPLDSQASP GLVLHAGAAT
- Characteristics
- This is a synthetic peptide designed for use in combination with anti- PDE4A Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- PDE4A (phosphodiesterase 4A, CAMP-Specific (PDE4A))
- Synonyms
- pde4 Peptide, dpde2 Peptide, pde46 Peptide, PDE4A Peptide, Pde4a Peptide, D9Ertd60e Peptide, Dpde2 Peptide, DPDE2 Peptide, PDE4 Peptide, PDE46 Peptide, PHOSA Peptide, phosphodiesterase 4A S homeolog Peptide, phosphodiesterase 4A, cAMP-specific Peptide, phosphodiesterase 4A Peptide, phosphodiesterase 4A, cAMP-specific (phosphodiesterase E2 dunce homolog, Drosophila) Peptide, cAMP-specific 3',5'-cyclic phosphodiesterase 4A Peptide, phosphodiesterase 4A, cAMP specific Peptide, phosphodiesterase 4C Peptide, pde4a.S Peptide, pde4a Peptide, PDE4A Peptide, LOC100009247 Peptide, Pde4a Peptide, PDE4C Peptide
- Background
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The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE4 subfamily. This PDE hydrolyzes the second messenger, cAMP, which is a regulator and mediator of a number of cellular responses to extracellular signals. Thus, by regulating the cellular concentration of cAMP, this protein plays a key role in many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Alias Symbols: PDE4, DPDE2, PDE46
Protein Size: 886 - Gene ID
- 5141
- NCBI Accession
- NM_001111307, NP_001104777
- UniProt
- P27815
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