Klotho beta (KLB) Peptide
-
- Target See all Klotho beta (KLB) products
- Klotho beta (KLB)
- Peptide Type
- Synthetic
- Origin
- Mammalian
-
Source
- Synthetic
- Application
- Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
- Sequence
- DAYTIRRGLF YVDFNSKQKE RKPKSSAHYY KQIIRENGFS LKESTPDVQG
- Characteristics
-
A synthetic peptide for use as a blocking control in assays to test for specificity of KLB antibody,
Alternative Names: Klotho Beta control peptide, Klotho Beta antibody Blocking Peptide, Anti-Klotho Beta Blocking Peptide, KLB Blocking Peptide, BKL Blocking Peptide, MGC142213 Blocking Peptide
-
-
- Application Notes
- Optimal conditions should be determined by the investigator
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
- Buffer
- PBS
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C long term.
-
- Target
- Klotho beta (KLB)
- Synonyms
- KLB Peptide, BKL Peptide, AV071179 Peptide, betaKlotho Peptide, Klb-ps1 Peptide, RGD1308227 Peptide, klotho beta Peptide, KLB Peptide, Klb Peptide
- Background
- KLB is a single-pass type III membrane protein. It contributes to the transcriptional repression of cholesterol 7-alpha-hydroxylase (CYP7A1), the rate-limiting enzyme in bile acid synthesis. KLB is probably inactive as a glycosidase. It increases the ability of FGFR1 and FGFR4 to bind FGF21.
- Molecular Weight
- 120 kDa
-