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Klotho beta (KLB) Peptide

KLB Reactivity: Mammalian Host: Synthetic BP, IHC, WB
Catalog No. ABIN937254
  • Target See all Klotho beta (KLB) products
    Klotho beta (KLB)
    Peptide Type
    Synthetic
    Origin
    Mammalian
    Source
    • 1
    Synthetic
    Application
    Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
    Sequence
    DAYTIRRGLF YVDFNSKQKE RKPKSSAHYY KQIIRENGFS LKESTPDVQG
    Characteristics
    A synthetic peptide for use as a blocking control in assays to test for specificity of KLB antibody,
    Alternative Names: Klotho Beta control peptide, Klotho Beta antibody Blocking Peptide, Anti-Klotho Beta Blocking Peptide, KLB Blocking Peptide, BKL Blocking Peptide, MGC142213 Blocking Peptide
  • Application Notes
    Optimal conditions should be determined by the investigator
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
    Buffer
    PBS
    Handling Advice
    Avoid repeated freeze/thaw cycles.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C long term.
  • Target
    Klotho beta (KLB)
    Synonyms
    KLB Peptide, BKL Peptide, AV071179 Peptide, betaKlotho Peptide, Klb-ps1 Peptide, RGD1308227 Peptide, klotho beta Peptide, KLB Peptide, Klb Peptide
    Background
    KLB is a single-pass type III membrane protein. It contributes to the transcriptional repression of cholesterol 7-alpha-hydroxylase (CYP7A1), the rate-limiting enzyme in bile acid synthesis. KLB is probably inactive as a glycosidase. It increases the ability of FGFR1 and FGFR4 to bind FGF21.
    Molecular Weight
    120 kDa
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