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Paired Immunoglobin-Like Type 2 Receptor alpha (PILRA) Peptide

PILRA Reactivity: Mammalian Host: Synthetic BP, WB, IHC
Catalog No. ABIN939476
  • Target See all PILRA products
    PILRA (Paired Immunoglobin-Like Type 2 Receptor alpha (PILRA))
    Peptide Type
    Synthetic
    Origin
    Mammalian
    Source
    • 1
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
    Sequence
    IPFSFYYPWE LATAPDVRIS WRRGHFHRQS FYSTRPPSIH KDYVNRLFLN
    Characteristics
    A synthetic peptide for use as a blocking control in assays to test for specificity of PILRA antibody,
    Alternative Names: PILRA control peptide, PILRA antibody Blocking Peptide, Anti-PILRA Blocking Peptide, Paired Immunoglobin-Like Type 2 Receptor Alpha Blocking Peptide, FDF03 Blocking Peptide
    Purification
    Purified
  • Application Notes
    Optimal conditions should be determined by the investigator
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
    Buffer
    PBS
    Handling Advice
    Avoid repeated freeze/thaw cycles.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C long term.
  • Target
    PILRA (Paired Immunoglobin-Like Type 2 Receptor alpha (PILRA))
    Synonyms
    PILRA Peptide, FDF03 Peptide, AV021745 Peptide, RGD1562847 Peptide, paired immunoglobin like type 2 receptor alpha Peptide, paired immunoglobulin-like type 2 receptor alpha Peptide, paired immunoglobin-like type 2 receptor alpha Peptide, PILRA Peptide, LOC489841 Peptide, Pilra Peptide
    Background
    Cell signaling pathways rely on a dynamic interaction between activating and inhibiting processes. SHP-1-mediated dephosphorylation of protein tyrosine residues is central to the regulation of several cell signaling pathways. Two types of inhibitory receptor superfamily members are immunoreceptor tyrosine-based inhibitory motif (ITIM)-bearing receptors and their non-ITIM-bearing, activating counterparts. Control of cell signaling via SHP-1 is thought to occur through a balance between PILRalpha-mediated inhibition and PILRbeta-mediated activation. This particular gene encodes the ITIM-bearing member of the receptor pair, which functions in the inhibitory role.
    Molecular Weight
    18 kDa
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