Paired Immunoglobin-Like Type 2 Receptor alpha (PILRA) Peptide
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- Target See all PILRA products
- PILRA (Paired Immunoglobin-Like Type 2 Receptor alpha (PILRA))
- Peptide Type
- Synthetic
- Origin
- Mammalian
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- Sequence
- IPFSFYYPWE LATAPDVRIS WRRGHFHRQS FYSTRPPSIH KDYVNRLFLN
- Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of PILRA antibody,
Alternative Names: PILRA control peptide, PILRA antibody Blocking Peptide, Anti-PILRA Blocking Peptide, Paired Immunoglobin-Like Type 2 Receptor Alpha Blocking Peptide, FDF03 Blocking Peptide - Purification
- Purified
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- Application Notes
- Optimal conditions should be determined by the investigator
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
- Buffer
- PBS
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C long term.
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- Target
- PILRA (Paired Immunoglobin-Like Type 2 Receptor alpha (PILRA))
- Synonyms
- PILRA Peptide, FDF03 Peptide, AV021745 Peptide, RGD1562847 Peptide, paired immunoglobin like type 2 receptor alpha Peptide, paired immunoglobulin-like type 2 receptor alpha Peptide, paired immunoglobin-like type 2 receptor alpha Peptide, PILRA Peptide, LOC489841 Peptide, Pilra Peptide
- Background
- Cell signaling pathways rely on a dynamic interaction between activating and inhibiting processes. SHP-1-mediated dephosphorylation of protein tyrosine residues is central to the regulation of several cell signaling pathways. Two types of inhibitory receptor superfamily members are immunoreceptor tyrosine-based inhibitory motif (ITIM)-bearing receptors and their non-ITIM-bearing, activating counterparts. Control of cell signaling via SHP-1 is thought to occur through a balance between PILRalpha-mediated inhibition and PILRbeta-mediated activation. This particular gene encodes the ITIM-bearing member of the receptor pair, which functions in the inhibitory role.
- Molecular Weight
- 18 kDa
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