Dysferlin (DYSF) Peptide
DYSF
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
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- Target See all Dysferlin (DYSF) products
- Dysferlin (DYSF)
- Peptide Type
- Synthetic
- Origin
- Mammalian
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- Sequence
- IVRAFGLQPK DPNGKCDPYI KISIGKKSVS DQDNYIPCTL EPVFGKMFEL
- Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of DYSF antibody,
Alternative Names: DYSF control peptide, DYSF antibody Blocking Peptide, Anti-DYSF Blocking Peptide, Dysferlin Limb Girdle Muscular Dystrophy 2B Blocking Peptide, FER1L1 Blocking Peptide, FLJ00175 Blocking Peptide, FLJ90168 Blocking Peptide, LGMD2B Blocking Peptide
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- Application Notes
- Optimal conditions should be determined by the investigator
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
- Buffer
- PBS
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C long term.
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- Target
- Dysferlin (DYSF)
- Synonyms
- DYSF Peptide, fb73b05 Peptide, wu:fb73b05 Peptide, si:rp71-50c18.1 Peptide, DKFZp459E1226 Peptide, 2310004N10Rik Peptide, AI604795 Peptide, D6Pas3 Peptide, mFLJ00175 Peptide, FER1L1 Peptide, LGMD2B Peptide, MMD1 Peptide, dysferlin Peptide, dysferlin, limb girdle muscular dystrophy 2B (autosomal recessive) Peptide, myoferlin Peptide, DYSF Peptide, dysf Peptide, LOC589501 Peptide, Dysf Peptide
- Background
- DYSF belongs to the ferlin family and is a skeletal muscle protein found associated with the sarcolemma. It is involved in muscle contraction and contains C2 domains that play a role in calcium-mediated membrane fusion events, suggesting that it may be involved in membrane regeneration and repair. In addition, DYSF binds caveolin-3, a skeletal muscle membrane protein which is important in the formation of caveolae. Specific mutations in this gene have been shown to cause autosomal recessive limb girdle muscular dystrophy type 2B (LGMD2B) as well as Miyoshi myopathy.
- Molecular Weight
- 237 kDa
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