Adrenergic, beta-2-, Receptor, Surface (ADRB2) (Middle Region) Peptide
ADRB2
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all beta 2 Adrenergic Receptor (ADRB2) products
- beta 2 Adrenergic Receptor (ADRB2) (Adrenergic, beta-2-, Receptor, Surface (ADRB2))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-ADRB2 antibody (Catalog #: AVARP00006_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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Adrenergic, beta-2-, Receptor, Surface (ADRB2) peptide (Ovalbumin)
ADRB2 Reactivity: Mouse Host: Synthetic WB, Imm, SDS
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- beta 2 Adrenergic Receptor (ADRB2) (Adrenergic, beta-2-, Receptor, Surface (ADRB2))
- Synonyms
- zgc:162188 Peptide, adrb2 Peptide, Adrb-2 Peptide, Badm Peptide, Gpcr7 Peptide, ADRB2R Peptide, ADRBR Peptide, B2AR Peptide, BAR Peptide, BETA2AR Peptide, adrenoceptor beta 2 Peptide, adrenoceptor beta 2, surface b Peptide, beta2-adrenergic receptor Peptide, adrenergic receptor, beta 2 Peptide, ADRB2 Peptide, adrb2b Peptide, LOC100136153 Peptide, Adrb2 Peptide
- Background
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This protein is beta-2-adrenergic receptor which is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor. This gene encodes beta-2-adrenergic receptor which is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor. This gene is intronless. Different polymorphic forms, point mutations, and/or downregulation of this gene are associated with nocturnal asthma, obesity and type 2 diabetes. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: ADRB2R, ADRBR, B2AR, BAR, BETA2AR
Protein Interaction Partner: EIF2B1,SLC9A3R1,SLC9A3R2,ADRB3,AKAP12,AKAP5,ARR3,ARRB1,CSK,EIF2B1,GNA11,GNA14,GNA15,GPRASP1,GRB2,GRK5,GRK6,HTR4,IL1B,INSR,KCNJ6,KCNJ9,NOS1,OPRD1,PRKCD,SLC9A3R1,SLC9A3R2,SRC,ADRB2,ADRBK1,AKAP12,Arrb2,EIF2B1,GRB2,GRK6,KCNJ3,KCNJ5,OPRD1,PPP3CA,SLC9A3R1,SLC9A3R2,SRC,UBC
Protein Size: 413 - Molecular Weight
- 46 kDa
- Gene ID
- 154
- NCBI Accession
- NM_000024, NP_000015
- UniProt
- P07550
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