Aryl-Hydrocarbon Receptor Repressor (AHRR) (Middle Region) Peptide
AHRR
Reactivity: Mouse
Host: Synthetic
BP, WB
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- Target See all AHRR products
- AHRR (Aryl-Hydrocarbon Receptor Repressor (AHRR))
- Protein Region
- Middle Region
- Origin
- Mouse
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- CLRGGPDLLD PKGTSGDREE EDQKHILRRS PGAWGQREMH KYSYGLETPV
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-Ahrr Antibody(ARP37012_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- AHRR (Aryl-Hydrocarbon Receptor Repressor (AHRR))
- Synonyms
- mKIAA1234 Peptide, AHH Peptide, AHHR Peptide, bHLHe77 Peptide, ahh Peptide, ahhr Peptide, bhlhe77 Peptide, ahrr2 Peptide, aryl-hydrocarbon receptor repressor Peptide, aryl hydrocarbon receptor repressor-like Peptide, uncharacterized LOC723045 Peptide, aryl-hydrocarbon receptor repressor L homeolog Peptide, aryl hydrocarbon receptor repressor Peptide, aryl-hydrocarbon receptor repressor b Peptide, Ahrr Peptide, AHRR Peptide, LOC529500 Peptide, LOC723045 Peptide, ahrr.L Peptide, LOC100455869 Peptide, ahrr Peptide, LOC100136487 Peptide, ahrrb Peptide
- Background
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Ahrr mediates dioxin toxicity and is involved in regulation of cell growth and differentiation. Ahrr represses the transcription activity of AHR by competing with this transcription factor for heterodimer formation with the ARNT and subsequently binding to the xenobiotic response element (XRE) sequence present in the promoter regulatory region of variety of genes. Ahrr represses CYP1A1 by binding the XRE sequence and recruiting ANKRA2, HDAC4 and/or HDAC5. Autoregulates its expression by associating with its own XRE site.
Alias Symbols: KIAA1234, mKIAA1234
Protein Size: 701 - Molecular Weight
- 78 kDa
- Gene ID
- 11624
- NCBI Accession
- NM_009644, NP_033774
- UniProt
- Q3U1U7
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