Aryl-Hydrocarbon Receptor Repressor (AHRR) (Middle Region) Peptide
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- Target See all AHRR products
- AHRR (Aryl-Hydrocarbon Receptor Repressor (AHRR))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-AHRR antibody (Catalog #: ARP39438_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- AHRR (Aryl-Hydrocarbon Receptor Repressor (AHRR))
- Synonyms
- mKIAA1234 Peptide, AHH Peptide, AHHR Peptide, bHLHe77 Peptide, ahh Peptide, ahhr Peptide, bhlhe77 Peptide, ahrr2 Peptide, aryl-hydrocarbon receptor repressor Peptide, aryl hydrocarbon receptor repressor-like Peptide, uncharacterized LOC723045 Peptide, aryl-hydrocarbon receptor repressor L homeolog Peptide, aryl hydrocarbon receptor repressor Peptide, aryl-hydrocarbon receptor repressor b Peptide, Ahrr Peptide, AHRR Peptide, LOC529500 Peptide, LOC723045 Peptide, ahrr.L Peptide, LOC100455869 Peptide, ahrr Peptide, LOC100136487 Peptide, ahrrb Peptide
- Background
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Dioxin is a teratogen that exerts its effects through the arylhydrocarbon receptor in conjunction with the receptor's binding partner, arylhydrocarbon receptor nuclear translocator. AHRR represses signal transduction by the arylhydrocarbon receptor by competing with the arylhydrocarbon receptor nuclear translocator for binding to the arylhydrocarbon receptor. Expression of the repressor is stimulated by the receptor/translocator heterodimer, thereby regulating receptor function through a negative feedback mechanism. In addition, AHRR can bind to nuclear factor kappa-B.Dioxin is a teratogen that exerts its effects through the arylhydrocarbon receptor in conjunction with the receptor's binding partner, arylhydrocarbon receptor nuclear translocator. The protein encoded by this gene represses signal transduction by the arylhydrocarbon receptor by competing with the arylhydrocarbon receptor nuclear translocator for binding to the arylhydrocarbon receptor. Expression of the repressor is stimulated by the receptor/translocator heterodimer, thereby regulating receptor function through a negative feedback mechanism. In addition, the encoded protein can bind to nuclear factor kappa-B. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: AHH, AHHR, KIAA1234, MGC167813, MGC176630, bHLHe77
Protein Interaction Partner: ARNT,ARNT
Protein Size: 719 - Molecular Weight
- 78 kDa
- Gene ID
- 57491
- NCBI Accession
- NM_020731, NP_065782
- UniProt
- A9YTQ3
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