Amyloid P Component, Serum (APCS) Peptide
APCS
Reactivity: Human, Drosophila melanogaster
Host: Synthetic
BP, IHC, WB
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- Target See all APCS products
- APCS (Amyloid P Component, Serum (APCS))
- Origin
- Human, Drosophila melanogaster
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-APCS antibody (Catalog #: ARP41962_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- APCS (Amyloid P Component, Serum (APCS))
- Synonyms
- PTX2 Peptide, SAP Peptide, Sap Peptide, APCS Peptide, FP Peptide, SAP(FP) Peptide, apcs Peptide, ptx2 Peptide, sap Peptide, amyloid P component, serum Peptide, serum amyloid P-component Peptide, amyloid P component, serum protein L homeolog Peptide, APCS Peptide, Apcs Peptide, apcs.L Peptide
- Background
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APCS is a glycoprotein, belonging to the pentraxin family of proteins, which has a characteristic pentameric organization. These family members have considerable sequence homology which is thought to be the result of gene duplication. The binding of the protein to proteins in the pathological amyloid cross-beta fold suggests its possible role as a chaperone. This protein is also thought to control the degradation of chromatin. It has been demonstrated that this protein binds to apoptotic cells at an early stage, which raises the possibility that it is involved in dealing with apoptotic cells in vivo.The protein encoded by this gene is a glycoprotein, belonging to the pentraxin family of proteins, which has a characteristic pentameric organization. These family members have considerable sequence homology which is thought to be the result of gene duplication. The binding of the encoded protein to proteins in the pathological amyloid cross-beta fold suggests its possible role as a chaperone. This protein is also thought to control the degradation of chromatin. It has been demonstrated that this protein binds to apoptotic cells at an early stage, which raises the possibility that it is involved in dealing with apoptotic cells in vivo. This gene has multiple polyadenylation sites.
Alias Symbols: MGC88159, PTX2, SAP
Protein Interaction Partner: APCS,C1QA,C4BPA,CALU,COL4A1,CRP,FCGR1A,FCGR2B,FCGR3A,FCGR3B,FN1,LAMA1,TG,APCS,C4BPA,CALU,CRP,FCGR1A,FCGR3A,FCGR3B,FN1
Protein Size: 223 - Molecular Weight
- 25 kDa
- Gene ID
- 325
- NCBI Accession
- NM_001639, NP_001630
- UniProt
- P02743
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