Cell Division Cycle 42 (GTP Binding Protein, 25kDa) (CDC42) Peptide
CDC42
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all CDC42 products
- CDC42 (Cell Division Cycle 42 (GTP Binding Protein, 25kDa) (CDC42))
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-CDC42 antibody (Catalog #: AVARP01017_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- CDC42 (Cell Division Cycle 42 (GTP Binding Protein, 25kDa) (CDC42))
- Synonyms
- CDC42Hs Peptide, G25K Peptide, AI747189 Peptide, AU018915 Peptide, cdc42a Peptide, wu:fb07d08 Peptide, wu:fj62g06 Peptide, zgc:63918 Peptide, Xcdc42 Peptide, cdc42hs Peptide, g25k Peptide, CDC42 Peptide, CG12530 Peptide, Cdc42Dm Peptide, D-CDC42 Peptide, D-Cdc42 Peptide, D-cdc42 Peptide, DCDC42 Peptide, DCdc42 Peptide, Dcdc42 Peptide, Dm Cdc42 Peptide, DmCDC42 Peptide, Dmcdc42 Peptide, Dmel\\CG12530 Peptide, cdc42 Peptide, cell division cycle 42 Peptide, Cell division control protein 42 homolog Peptide, cell division control protein 42 homolog Peptide, cell division cycle 42 L homeolog Peptide, CG12530 gene product from transcript CG12530-RC Peptide, Rho family GTPase Peptide, CDC42 Peptide, Cdc42 Peptide, cdc42 Peptide, LOC100636735 Peptide, LOC100637699 Peptide, LOC100638834 Peptide, cdc42.L Peptide
- Background
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CDC42 is a small GTPase of the Rho-subfamily, which regulates signaling pathways that control diverse cellular functions including cell morphology, migration, endocytosis and cell cycle progression. This protein is highly similar to Saccharomyces cerevisiae Cdc 42, and is able to complement the yeast cdc42-1 mutant. The product of oncogene Dbl was reported to specifically catalyze the dissociation of GDP from this protein. This protein could regulate actin polymerization through its direct binding to Neural Wiskott-Aldrich syndrome protein (N-WASP), which subsequently activates Arp2/3 complex. Alternative splicing of this gene results in multiple transcript variants.The protein encoded by this gene is a small GTPase of the Rho-subfamily, which regulates signaling pathways that control diverse cellular functions including cell morphology, migration, endocytosis and cell cycle progression. This protein is highly similar to Saccharomyces cerevisiae Cdc 42, and is able to complement the yeast cdc42-1 mutant. The product of oncogene Dbl was reported to specifically catalyze the dissociation of GDP from this protein. This protein could regulate actin polymerization through its direct binding to Neural Wiskott-Aldrich syndrome protein (N-WASP), which subsequently activates Arp2/3 complex. Alternative splicing of this gene results in multiple transcript variants.
Alias Symbols: CDC42Hs, G25K
Protein Interaction Partner: WAS,CDC42EP2,CDC42EP3,ITSN1,MCF2L,WAS,ACTR3,ANXA2,ARHGAP1,ARHGAP31,ARHGDIA,ARHGDIB,ARHGDIG,ARHGEF6,ARHGEF7,BAIAP2,BNIP2,C14orf1,C1orf103,CASP3,CASP7,CDC42BPG,CDC42EP1,CDC42EP2,CDC42EP3,CDC42EP5,CDC42SE1,CSPG4,DEF6,DOCK7,DOCK8,DOCK9,EEF1G,EIF2AK2,ERRFI1,FGD1,FLNA,FNBP1,GDI1,GEFT,IQGAP1,IQGAP2,ITSN1,KAT5,KTN1,LCK,MAP3K10,MAP3K11,MAP3K4,MARK4,MCF2L,METAP2,MYO9A,NCF2,OCRL,OPHN1,PAK1,PAK2,PAK4,PAK6,PAK7,PARD3,PARD6A,PARD6B,PARD6G,PDE6D,PGGT1B,PIK3R1,PLD1,PLEKHG2,PRKCA,PRKCG,PRKCI,PRKCZ,RAC2,RHOJ,RPS6KB1,SRGAP1,STAU1,TBC1D3F,TNK2,TP53,TRIP10,UBR1,UNC119,VAV1,WAS,WASF1,WASF2,ARHGAP1,ARHGAP1,ARHGAP10,ARHGAP17,ARHGAP26,ARHGAP27,ARHGAP29,ARHGAP32,ARHGAP8,ARHGDIA,ARHGDIG,ARHGEF6,ARHGEF7,BAIAP2,BCR,BNIP2,BNIP2,BNIP2,BNIP2,BNIPL,C14orf1,C1orf103,CDC42,CDC42BPG,CDC42EP1,CDC42EP2,CDC42EP3,CDC42EP5,CDC42SE1,CDC42SE2,CLIP1,CNTNAP1,CSPG4,DEF6,DEF6,DOCK8,DOCK9,Diap3,EEF1G,ERRFI1,FGD1,FNBP1L,GDI1,GEFT,GOPC,IQGAP1,IQGAP2,ITSN1,KAT5,Kin,MAP3K10,MAP3K11,MAP3K4,MCF2,MCF2L,NCF2,Net1,OPHN1,PAK1,PAK1,PAK1,PAK2,PAK4,PAK6,PAK7,PARD6A,PARD6B,PARD6G,PDE6D,PLD1,PLEKHG2,RAC1,RICH2,Rock1,TBC1D3F,TNK2,TP53,TRIP10,UBR1,UNC119,VAV1,WAS,WAS,WASL,tax
Protein Size: 191 - Molecular Weight
- 21 kDa
- Gene ID
- 998
- NCBI Accession
- NM_001791, NP_001782
- UniProt
- P60953
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