CASP8 and FADD-Like Apoptosis Regulator (CFLAR) Peptide
CFLAR
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all FLIP (CFLAR) products
- FLIP (CFLAR) (CASP8 and FADD-Like Apoptosis Regulator (CFLAR))
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-CFLAR antibody (Catalog #: AVARP00022_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- FLIP (CFLAR) (CASP8 and FADD-Like Apoptosis Regulator (CFLAR))
- Synonyms
- Clarp1 Peptide, cflar Peptide, CFLAR Peptide, FLIP Peptide, CASH Peptide, CASP8AP1 Peptide, CLARP Peptide, Casper Peptide, FLAME Peptide, FLAME-1 Peptide, FLAME1 Peptide, I-FLICE Peptide, MRIT Peptide, c-FLIP Peptide, c-FLIPL Peptide, c-FLIPR Peptide, c-FLIPS Peptide, 2310024N18Rik Peptide, A430105C05Rik Peptide, Cash Peptide, ENSMUSG00000072980 Peptide, Flip Peptide, Gm9845 Peptide, c-Flip Peptide, CASP8 and FADD-like apoptosis regulator a Peptide, CASP8 and FADD like apoptosis regulator Peptide, CASP8 and FADD like apoptosis regulator S homeolog Peptide, CASP8 and FADD-like apoptosis regulator Peptide, cflara Peptide, CFLAR Peptide, cflar Peptide, cflar.S Peptide, Cflar Peptide
- Background
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CFLAR might contribute to the carcinogenesis and aggressiveness of endometrial carcinoma and might be a useful prognostic factor in the tumor. CFLAR is specially overexpressed in colon cancers and it might contribute to carcinogenesis of normal colonic mucosa.
Alias Symbols: CASH, FLIP, MRIT, CLARP, FLAME, Casper, FLAME1, c-FLIP, FLAME-1, I-FLICE, c-FLIPL, c-FLIPR, c-FLIPS, CASP8AP1
Protein Interaction Partner: CASP3,CASP8,FADD,BCL2L1,CASP3,CASP8,DAXX,FADD,BCL2L1,CASP10,CASP2,CASP3,CASP6,CASP7,CASP8,DAXX,DEDD,DEDD2,FADD,IKBKB,MAP2K4,MAP2K7,NFKB1,PSEN2,RAF1,RIPK1,RIPK2,TNFRSF10B,TRAF1,TRAF2,BCL2L1,CASP10,CASP3,CASP8,CFLAR,DEDD,DEDD2,DOK2,FADD,FAS,ITCH,MAP3K14,NOD1,NOL3,RAF1,RIPK1,RIPK2,SF3B3,TNFRSF10A,TNFRSF10B,TP53,TRAF1,TRAF2,TRAF3,UBC
Protein Size: 480 - Molecular Weight
- 55 kDa
- Gene ID
- 8837
- NCBI Accession
- NM_003879, NP_003870
- UniProt
- O15519
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