Deleted in Azoospermia 2 (DAZ2) Peptide
DAZ2
Reactivity: Human
Host: Synthetic
BP, IHC, WB
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- Target See all DAZ2 products
- DAZ2 (Deleted in Azoospermia 2 (DAZ2))
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-DAZ2 antibody (Catalog #: ARP40250_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- DAZ2 (Deleted in Azoospermia 2 (DAZ2))
- Synonyms
- pDP1678 Peptide, DAZ2 Peptide, deleted in azoospermia 2 Peptide, deleted in azoospermia protein 2 Peptide, DAZ2 Peptide, LOC738583 Peptide
- Background
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DAZ2 is a member of the DAZ family and is a candidate for the human Y-chromosomal azoospermia factor (AZF). This RNA-binding protein is important for spermatogenesis.This gene is a member of the DAZ gene family and is a candidate for the human Y-chromosomal azoospermia factor (AZF). Its expression is restricted to premeiotic germ cells, particularly in spermatogonia. It encodes an RNA-binding protein that is important for spermatogenesis. Four copies of this gene are found on chromosome Y within palindromic duplications, one pair of genes is part of the P2 palindrome and the second pair is part of the P1 palindrome. Each gene contains a 2.4 kb repeat including a 72-bp exon, called the DAZ repeat, the number of DAZ repeats is variable and there are several variations in the sequence of the DAZ repeat. Each copy of the gene also contains a 10.8 kb region that may be amplified, this region includes five exons that encode an RNA recognition motif (RRM) domain. This gene contains one copy of the 10.8 kb repeat. Alternative splicing results in multiple transcript variants encoding different isoforms.
Alias Symbols: pDP1678
Protein Interaction Partner: PUM2
Protein Size: 534 - Molecular Weight
- 59 kDa
- Gene ID
- 57055
- NCBI Accession
- NM_001005785, NP_001005785
- UniProt
- Q2KHN6
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