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Dihydrolipoamide Branched Chain Transacylase E2 (DBT) (N-Term) Peptide

DBT Reactivity: Human Host: Synthetic BP, WB, IHC
Catalog No. ABIN975611
  • Target See all DBT products
    DBT (Dihydrolipoamide Branched Chain Transacylase E2 (DBT))
    Protein Region
    N-Term
    Origin
    Human
    Source
    • 2
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-DBT antibody (Catalog #: ARP51995_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    DBT (Dihydrolipoamide Branched Chain Transacylase E2 (DBT))
    Synonyms
    BCATE2 Peptide, BCKAD-E2 Peptide, BCKADE2 Peptide, E2 Peptide, E2B Peptide, D3Wsu60e Peptide, im:7147214 Peptide, zgc:103768 Peptide, E2b Peptide, dihydrolipoamide branched chain transacylase E2 Peptide, hypothetical protein Peptide, dihydrolipoamide branched chain transacylase E2 L homeolog Peptide, DBT Peptide, dbt Peptide, CpipJ_CPIJ006326 Peptide, BDBG_05874 Peptide, NAEGRDRAFT_78509 Peptide, VDBG_04820 Peptide, PGTG_17722 Peptide, Dbt Peptide, dbt.L Peptide
    Target Type
    Viral Protein
    Background
    The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO2. It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).The branched-chain alpha-keto acid dehydrogenase complex (BCKD) is an inner-mitochondrial enzyme complex involved in the breakdown of the branched-chain amino acids isoleucine, leucine, and valine. The BCKD complex is thought to be composed of a core of 24 transacylase (E2) subunits, and associated decarboxylase (E1), dehydrogenase (E3), and regulatory subunits. This gene encodes the transacylase (E2) subunit. Mutations in this gene result in maple syrup urine disease, type 2. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

    Alias Symbols: BCATE2, E2, E2B, MGC9061

    Protein Interaction Partner: ADI1,USP16

    Protein Size: 482
    Molecular Weight
    46 kDa
    Gene ID
    1629
    NCBI Accession
    NM_001918, NP_001909
    UniProt
    P11182
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