Dihydrolipoamide Branched Chain Transacylase E2 (DBT) (N-Term) Peptide
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- Target See all DBT products
- DBT (Dihydrolipoamide Branched Chain Transacylase E2 (DBT))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-DBT antibody (Catalog #: ARP51995_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- DBT (Dihydrolipoamide Branched Chain Transacylase E2 (DBT))
- Synonyms
- BCATE2 Peptide, BCKAD-E2 Peptide, BCKADE2 Peptide, E2 Peptide, E2B Peptide, D3Wsu60e Peptide, im:7147214 Peptide, zgc:103768 Peptide, E2b Peptide, dihydrolipoamide branched chain transacylase E2 Peptide, hypothetical protein Peptide, dihydrolipoamide branched chain transacylase E2 L homeolog Peptide, DBT Peptide, dbt Peptide, CpipJ_CPIJ006326 Peptide, BDBG_05874 Peptide, NAEGRDRAFT_78509 Peptide, VDBG_04820 Peptide, PGTG_17722 Peptide, Dbt Peptide, dbt.L Peptide
- Target Type
- Viral Protein
- Background
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The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO2. It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).The branched-chain alpha-keto acid dehydrogenase complex (BCKD) is an inner-mitochondrial enzyme complex involved in the breakdown of the branched-chain amino acids isoleucine, leucine, and valine. The BCKD complex is thought to be composed of a core of 24 transacylase (E2) subunits, and associated decarboxylase (E1), dehydrogenase (E3), and regulatory subunits. This gene encodes the transacylase (E2) subunit. Mutations in this gene result in maple syrup urine disease, type 2. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: BCATE2, E2, E2B, MGC9061
Protein Interaction Partner: ADI1,USP16
Protein Size: 482 - Molecular Weight
- 46 kDa
- Gene ID
- 1629
- NCBI Accession
- NM_001918, NP_001909
- UniProt
- P11182
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