DEXH (Asp-Glu-X-His) Box Polypeptide 58 (DHX58) (N-Term) Peptide
DHX58
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all DHX58 products
- DHX58 (DEXH (Asp-Glu-X-His) Box Polypeptide 58 (DHX58))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-DHX58 antibody (Catalog #: ARP36500_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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DEXH (Asp-Glu-X-His) Box Polypeptide 58 (DHX58) peptide
DHX58 Reactivity: Human Host: Synthetic BP, Imm
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- DHX58 (DEXH (Asp-Glu-X-His) Box Polypeptide 58 (DHX58))
- Synonyms
- MGC82787 Peptide, DHX58 Peptide, lgp2 Peptide, D11LGP2 Peptide, D11lgp2e Peptide, LGP2 Peptide, RLR-3 Peptide, B430001I08Rik Peptide, D11Lgp2e Peptide, LPG2 Peptide, Lgp2 Peptide, RGD1310093 Peptide, DEXH-box helicase 58 L homeolog Peptide, DExH-box helicase 58 Peptide, probable ATP-dependent RNA helicase DHX58 Peptide, DEXH (Asp-Glu-X-His) box polypeptide 58 Peptide, DEXH-box helicase 58 Peptide, dhx58.L Peptide, DHX58 Peptide, dhx58 Peptide, LOC100566102 Peptide, Dhx58 Peptide
- Background
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DHX58 is the negative regulator of host innate immune defense against viruses. The repressor domain of DHX58 interacts with DDX58 and negatively regulates DDX58-mediated signaling. Binds dsRNA produced during viral replication, in particuliar HCV RNA. Bin
Alias Symbols: D11LGP2, D11lgp2e, LGP2
Protein Interaction Partner: AP2B1,AP2B1
Protein Size: 678 - Molecular Weight
- 76 kDa
- Gene ID
- 79132
- NCBI Accession
- NM_024119, NP_077024
- UniProt
- Q96C10
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