DNA Repair Protein Complementing XP-G Cells (ERCC5) Peptide
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- Target See all ERCC5 products
- ERCC5 (DNA Repair Protein Complementing XP-G Cells (ERCC5))
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-ERCC5 antibody (Catalog #: ARP54287_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- ERCC5 (DNA Repair Protein Complementing XP-G Cells (ERCC5))
- Synonyms
- COFS3 Peptide, ERCM2 Peptide, UVDR Peptide, XPG Peptide, XPGC Peptide, cofs3 Peptide, ercm2 Peptide, uvdr Peptide, xpg Peptide, xpgc Peptide, Xpg Peptide, ERCC excision repair 5, endonuclease Peptide, excision repair cross-complementation group 5 L homeolog Peptide, excision repair cross-complementing rodent repair deficiency, complementation group 5 Peptide, ERCC5 Peptide, ercc5.L Peptide, Ercc5 Peptide
- Background
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Excision repair cross-complementing rodent repair deficiency, complementation group 5 (xeroderma pigmentosum, complementation group G) is involved in excision repair of UV-induced DNA damage. Mutations cause Cockayne syndrome, which is characterized by severe growth defects, mental retardation, and cachexia. Excision repair cross-complementing rodent repair deficiency, complementation group 5 (xeroderma pigmentosum, complementation group G) is involved in excision repair of UV-induced DNA damage. Mutations cause Cockayne syndrome, which is characterized by severe growth defects, mental retardation, and cachexia. Multiple alternatively spliced transcript variants encoding distinct isoforms have been described, but the biological validity of all variants has not been determined. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: COFS3, ERCM2, UVDR, XPG, XPGC
Protein Interaction Partner: ERCC2,ERCC6,EWSR1,GTF2H1,GTF2H4,NTHL1,PCNA,POLR2A,CDK7,ERCC2,ERCC3,NTHL1,PCNA,TAF10
Protein Size: 1186 - Molecular Weight
- 133 kDa
- Gene ID
- 2073
- NCBI Accession
- NM_000123, NP_000114
- UniProt
- P28715
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