Kallikrein 6 (KLK6) Peptide
KLK6
Reactivity: Human
Host: Synthetic
BP, IHC, WB
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- Target See all Kallikrein 6 (KLK6) products
- Kallikrein 6 (KLK6)
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-KLK6 antibody (Catalog #: ARP33888_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- Kallikrein 6 (KLK6)
- Synonyms
- Bssp Peptide, Klk7 Peptide, PRSS18 Peptide, PRSS9 Peptide, SP59 Peptide, hK6 Peptide, Prss9 Peptide, AI849898 Peptide, BSP Peptide, Klk29 Peptide, MSP Peptide, Prss18 Peptide, neurosin Peptide, kallikrein related peptidase 6 Peptide, kallikrein related-peptidase 6 Peptide, kallikrein-6 Peptide, KLK6 Peptide, Klk6 Peptide, LOC100716801 Peptide
- Background
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Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. The gene that encodes KLK6 protein is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. KLK6 is regulated by steroid hormones. In tissue culture, the enzyme has been found to generate amyloidogenic fragments from the amyloid precursor protein, suggesting a potential for involvement in Alzheimer's disease.Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. The encoded enzyme is regulated by steroid hormones. In tissue culture, the enzyme has been found to generate amyloidogenic fragments from the amyloid precursor protein, suggesting a potential for involvement in Alzheimer's disease. Multiple alternatively spliced transcript variants that encode different isoforms have been identified for this gene.
Alias Symbols: Bssp, Klk7, MGC9355, NEUROSIN, PRSS18, PRSS9, SP59, ZYME, hK6
Protein Interaction Partner: SERPINC1,SERPINF2,SNCA
Protein Size: 244 - Molecular Weight
- 25 kDa
- Gene ID
- 5653
- NCBI Accession
- NM_001012964, NP_001012982
- UniProt
- Q92876
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