Left-Right Determination Factor 2 (LEFTY2) Peptide
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- Target See all LEFTY2 products
- LEFTY2 (Left-Right Determination Factor 2 (LEFTY2))
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-LEFTY2 antibody (Catalog #: ARP42107_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- LEFTY2 (Left-Right Determination Factor 2 (LEFTY2))
- Synonyms
- EBAF Peptide, LEFTA Peptide, LEFTYA Peptide, TGFB4 Peptide, AI450052 Peptide, Ebaf Peptide, Leftb Peptide, Stra3 Peptide, Tgfb4 Peptide, lefty Peptide, lefty-1 Peptide, atv2 Peptide, cb720 Peptide, fe38b03 Peptide, wu:fe38b03 Peptide, 6030463A22Rik Peptide, AV214969 Peptide, Lefta Peptide, Ebaf2 Peptide, left-right determination factor 2 Peptide, left right determination factor 1 Peptide, lefty2 Peptide, Left-right determination factor 2 Peptide, left-right determination factor 2-like Peptide, LEFTY2 Peptide, Lefty1 Peptide, lft2 Peptide, Lefty2 Peptide, LOC699676 Peptide, LOC100232580 Peptide
- Background
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LEFTY2 is a member of the TGF-beta family of proteins. The protein is secreted and plays a role in left-right asymmetry determination of organ systems during development. The protein may also play a role in endometrial bleeding. Mutations in its gene have been associated with left-right axis malformations, particularly in the heart and lungs. Some types of infertility have been associated with dysregulated expression of its gene in the endometrium.This gene encodes a member of the TGF-beta family of proteins. The encoded protein is secreted and plays a role in left-right asymmetry determination of organ systems during development. The protein may also play a role in endometrial bleeding. Mutations in this gene have been associated with left-right axis malformations, particularly in the heart and lungs. Some types of infertility have been associated with dysregulated expression of this gene in the endometrium. Alternative processing of this protein can yield three different products. This gene is closely linked to both a related family member and a related pseudogene.
Alias Symbols: EBAF, LEFTA, LEFTYA, MGC46222, TGFB4
Protein Size: 366 - Molecular Weight
- 40 kDa
- Gene ID
- 7044
- NCBI Accession
- NM_003240, NP_003231
- UniProt
- O00292
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