Methionine Adenosyltransferase I, alpha (MAT1A) Peptide
MAT1A
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all MAT1A products
- MAT1A (Methionine Adenosyltransferase I, alpha (MAT1A))
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-MAT1A antibody (Catalog #: ARP41399_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- MAT1A (Methionine Adenosyltransferase I, alpha (MAT1A))
- Synonyms
- MAT Peptide, MATA1 Peptide, SAMS Peptide, SAMS1 Peptide, AdoMet Peptide, SADE Peptide, SAS Peptide, AI046368 Peptide, Ams Peptide, wu:fi35e01 Peptide, zgc:55442 Peptide, methionine adenosyltransferase 1A Peptide, methionine adenosyltransferase I, alpha Peptide, MAT1A Peptide, Mat1a Peptide, mat1a Peptide
- Background
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MAT1A catalyzes a two-step reaction that involves the transfer of the adenosyl moiety of ATP to methionine to form S-adenosylmethionine and tripolyphosphate, which is subsequently cleaved to PPi and Pi. S-adenosylmethionine is the source of methyl groups for most biological methylations. MAT1A is found as a homotetramer (MAT I) or a homodimer (MAT III) whereas a third form, MAT II (gamma), is encoded by the MAT2A gene. Mutations in its gene are associated with methionine adenosyltransferase deficiency.This gne encodes methionine adenosyltransferase I (alpha isoform), which catalyzes the formation of S-adenosylmethionine from methionine and ATP. Methionine adenosyltransferase deficiency is caused by recessive and dominant mutations, the latter identified in autosomal dominant persistant hypermethioninemia.
Alias Symbols: MAT, MATA1, SAMS, SAMS1
Protein Size: 395 - Molecular Weight
- 44 kDa
- Gene ID
- 4143
- NCBI Accession
- NM_000429, NP_000420
- UniProt
- Q00266
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