Nuclear Receptor Subfamily 1, Group H, Member 4 (NR1H4) (Middle Region) Peptide
NR1H4
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all NR1H4 products
- NR1H4 (Nuclear Receptor Subfamily 1, Group H, Member 4 (NR1H4))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- CRLRKCKEMG MLAECMYTGL LTEIQCKSKR LRKNVKQHAD QTVNEDSEGR
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-NR1H4 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- NR1H4 (Nuclear Receptor Subfamily 1, Group H, Member 4 (NR1H4))
- Synonyms
- zgc:110190 Peptide, zgc:92742 Peptide, NR1H4 Peptide, BAR Peptide, FXR Peptide, HRR-1 Peptide, HRR1 Peptide, RIP14 Peptide, AI957360 Peptide, Fxr Peptide, Rxrip14 Peptide, nuclear receptor subfamily 1, group H, member 5 S homeolog Peptide, nuclear receptor subfamily 1, group H, member 4 Peptide, nuclear receptor subfamily 1 group H member 4 Peptide, nr1h5.S Peptide, nr1h4 Peptide, NR1H4 Peptide, Nr1h4 Peptide
- Background
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This gene encodes a ligand-activated transcription factor, which shares structural features in common with nuclear hormone receptor family, such as a DNA-binding domain that targets the receptor to specific DNA sequences, and a ligand-binding domain, which interacts directly with the ligand and contains a ligand-dependent transcriptional activation domain. This protein functions as a receptor for bile acids, and when bound to bile acids, regulates the expression of genes involved in bile acid synthesis and transport. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Alias Symbols: NR1H4,BAR, FXR, HRR1, RIP14,
Protein Size: 486 - Molecular Weight
- 54 kDa
- Gene ID
- 9971
- UniProt
- Q96RI1
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