Nuclear Receptor Subfamily 1, Group H, Member 4 (NR1H4) (Middle Region) Peptide
NR1H4
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all NR1H4 products
- NR1H4 (Nuclear Receptor Subfamily 1, Group H, Member 4 (NR1H4))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-NR1H4 antibody (Catalog #: ARP45626_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- NR1H4 (Nuclear Receptor Subfamily 1, Group H, Member 4 (NR1H4))
- Synonyms
- zgc:110190 Peptide, zgc:92742 Peptide, NR1H4 Peptide, BAR Peptide, FXR Peptide, HRR-1 Peptide, HRR1 Peptide, RIP14 Peptide, AI957360 Peptide, Fxr Peptide, Rxrip14 Peptide, nuclear receptor subfamily 1, group H, member 5 S homeolog Peptide, nuclear receptor subfamily 1, group H, member 4 Peptide, nuclear receptor subfamily 1 group H member 4 Peptide, nr1h5.S Peptide, nr1h4 Peptide, NR1H4 Peptide, Nr1h4 Peptide
- Background
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NR1H4 is the receptor for bile acids such as chenodeoxycholic acid, lithocholic acid and deoxycholic acid. NR1H4 represses the transcription of the cholesterol 7-alpha-hydroxylase gene (CYP7A1) through the induction of NR0B2 or FGF19 expression, via two d
Alias Symbols: BAR, FXR, HRR-1, HRR1, MGC163445, RIP14
Protein Interaction Partner: CASP8,ESR1,GAPDH,NCOA1,NCOR2,PPARGC1A,RXRA,RXRG,SMARCD3,CASP8,NCOA1,PPARGC1A,RXRA,SMARCD1
Protein Size: 472 - Molecular Weight
- 54 kDa
- Gene ID
- 9971
- NCBI Accession
- NM_005123, NP_005114
- UniProt
- B6ZGS9
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