Nuclear Receptor Subfamily 3, Group C, Member 2 (NR3C2) Peptide
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- Target See all NR3C2 products
- NR3C2 (Nuclear Receptor Subfamily 3, Group C, Member 2 (NR3C2))
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-NR3C2 antibody (Catalog #: ARP45599_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- NR3C2 (Nuclear Receptor Subfamily 3, Group C, Member 2 (NR3C2))
- Synonyms
- mr Peptide, si:ch211-189l17.1 Peptide, LOC100302443 Peptide, NR3C2 Peptide, LOC443144 Peptide, MLR Peptide, MR Peptide, MCR Peptide, NR3C2VIT Peptide, Mlr Peptide, mlr Peptide, nuclear receptor subfamily 3, group C, member 2 Peptide, nuclear receptor subfamily 3 group C member 2 Peptide, mineralocorticoid receptor Peptide, nuclear receptor subfamily 3 group C member 2 L homeolog Peptide, nr3c2 Peptide, NR3C2 Peptide, LOC443144 Peptide, Nr3c2 Peptide, nr3c2.L Peptide
- Background
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NR3C2 is a receptor for both mineralocorticoids (MC) such as aldosterone and glucocorticoids (GC) such as corticosterone or cortisol. It binds to mineralocorticoid response elements (MRE) and transactivates target genes. The effect of MC is to increase ion and water transport and thus raise extracellular fluid volume and blood pressure and lower potassium levels.
Alias Symbols: MCR, MGC133092, MLR, MR, NR3C2VIT
Protein Interaction Partner: ACTA1,ACTG1,AR,FKBP4,HSP90AA1,HSPA4,NR3C1,PIAS1,PIAS3,PROX1,PTGES3,TRIM24,NR3C1,PTGES3,TRIM24
Protein Size: 984 - Molecular Weight
- 107 kDa
- Gene ID
- 4306
- NCBI Accession
- NM_000901, NP_000892
- UniProt
- P08235
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