Proprotein Convertase Subtilisin/kexin Type 2 (PCSK2) (Middle Region) Peptide
PCSK2
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all PCSK2 products
- PCSK2 (Proprotein Convertase Subtilisin/kexin Type 2 (PCSK2))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- LASTFSNGRK RNPEAGVATT DLYGNCTLRH SGTSAAAPEA AGVFALALEA
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-PCSK2 Antibody(ARP59552_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- PCSK2 (Proprotein Convertase Subtilisin/kexin Type 2 (PCSK2))
- Synonyms
- NEC 2 Peptide, NEC-2 Peptide, NEC2 Peptide, PC2 Peptide, SPC2 Peptide, PCSK2 Peptide, 6330411F23Rik Peptide, AI839700 Peptide, Nec-2 Peptide, Nec2 Peptide, Phpp-2 Peptide, pc2 Peptide, nec2 Peptide, spc2 Peptide, pcsk2 Peptide, pcsk2-A Peptide, proprotein convertase subtilisin/kexin type 2 Peptide, proprotein convertase subtilisin/kexin type 2 L homeolog Peptide, PCSK2 Peptide, pcsk2 Peptide, Pcsk2 Peptide, pcsk2.L Peptide
- Background
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This gene encodes a member of the subtilisin-like proprotein convertase family. These enzymes process latent precursor proteins into their biologically active products. The encoded protein plays a critical role in hormone biosynthesis by processing a variety of prohormones including proinsulin, proopiomelanocortin and proluteinizing-hormone-releasing hormone. Single nucleotide polymorphisms in this gene may increase susceptibility to myocardial infarction and type 2 diabetes. This gene may also play a role in tumor development and progression. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Alias Symbols: NEC2, PC2, SPC2, NEC 2, NEC-2
Protein Interaction Partner: IAPP,PMCH,SCG5,THRA
Protein Size: 638 - Molecular Weight
- 58 kDa
- Gene ID
- 5126
- NCBI Accession
- NM_002594, NP_002585
- UniProt
- Q5REC2
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