phosphofructokinase, Platelet (PFKP) (C-Term) Peptide
PFKP
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all PFKP products
- PFKP (phosphofructokinase, Platelet (PFKP))
- Protein Region
- C-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- EWITAKLKEA RGRGKKFTTD DSICVLGISK RNVIFQPVAE LKKQTDFEHR
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-PFKP Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- PFKP (phosphofructokinase, Platelet (PFKP))
- Synonyms
- pfk Peptide, pfk-c Peptide, pfkf Peptide, PFKP Peptide, PFK-C Peptide, PFKF Peptide, 1200015H23Rik Peptide, 9330125N24Rik Peptide, PFKM Peptide, phosphofructokinase, platelet Peptide, phosphofructokinase, platelet S homeolog Peptide, ATP-dependent 6-phosphofructokinase, platelet type Peptide, pfkp Peptide, PFKP Peptide, pfkp.S Peptide, LOC100549777 Peptide, Pfkp Peptide
- Background
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The PFKP gene encodes the platelet isoform of phosphofructokinase (PFK) (ATP:D-fructose-6-phosphate-1-phosphotransferase, EC 2.7.1.11). PFK catalyzes the irreversible conversion of fructose-6-phosphate to fructose-1,6-bisphosphate and is a key regulatory enzyme in glycolysis. The PFKP gene, which maps to chromosome 10p, is also expressed in fibroblasts. See also the muscle (PFKM, MIM 610681) and liver (PFKL, MIM 171860) isoforms of phosphofructokinase, which map to chromosomes 12q13 and 21q22, respectively. Vora (1981) [PubMed 6451249] determined that full tetrameric phophofructokinase enzyme expressed in platelets can be composed of subunits P4, P3L, and P2L2.
Alias Symbols: FLJ40226, PFK-C, PFKF
Protein Interaction Partner: DYNLL1,DMWD,GBAS,MCC,UBC,WIPI2
Protein Size: 784 - Molecular Weight
- 85 kDa
- Gene ID
- 5214
- NCBI Accession
- NM_002627, NP_002618
- UniProt
- Q01813
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