Regulator of G-Protein Signaling 10 (RGS10) Peptide
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- Target See all RGS10 products
- RGS10 (Regulator of G-Protein Signaling 10 (RGS10))
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Flow Cytometry (FACS), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-RGS10 antibody (Catalog #: AVARP09013_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- RGS10 (Regulator of G-Protein Signaling 10 (RGS10))
- Synonyms
- MGC82511 Peptide, RGS10 Peptide, 2310010N19Rik Peptide, regulator of G-protein signaling 10 Peptide, regulator of G-protein signaling 10 L homeolog Peptide, regulator of G protein signaling 10 Peptide, regulator of G-protein signalling 10 Peptide, RGS10 Peptide, rgs10.L Peptide, rgs10 Peptide, Rgs10 Peptide
- Background
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Regulator of G protein signaling (RGS) family members are regulatory molecules that act as GTPase activating proteins (GAPs) for G alpha subunits of heterotrimeric G proteins. RGS proteins are able to deactivate G protein subunits of the Gi alpha, Go alpha and Gq alpha subtypes. They drive G proteins into their inactive GDP-bound forms. Regulator of G protein signaling 10 belongs to this family. All RGS proteins share a conserved 120-amino acid sequence termed the RGS domain. This protein associates specifically with the activated forms of the two related G-protein subunits, G-alphai3 and G-alphaz but fails to interact with the structurally and functionally distinct G-alpha subunits. Regulator of G protein signaling 10 protein is localized in the nucleus. Two transcript variants encoding different isoforms have been found for this gene.
Protein Interaction Partner: CALM1,GNAI1,GNAI3,GNAO1,GNAZ,GNRHR,PRKACA,ACP6,EIF6,GNAI1,GNAI3,GNAZ,SAP18
Protein Size: 181 - Molecular Weight
- 21 kDa
- Gene ID
- 6001
- NCBI Accession
- NM_001005339, NP_001005339
- UniProt
- Q96GN0
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