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Regulator of G-Protein Signaling 10 (RGS10) Peptide

RGS10 Reactivity: Human Host: Synthetic BP, FACS, WB
Catalog No. ABIN982919
  • Target See all RGS10 products
    RGS10 (Regulator of G-Protein Signaling 10 (RGS10))
    Origin
    Human
    Source
    • 2
    Synthetic
    Application
    Blocking Peptide (BP), Flow Cytometry (FACS), Western Blotting (WB)
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-RGS10 antibody (Catalog #: AVARP09013_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    RGS10 (Regulator of G-Protein Signaling 10 (RGS10))
    Synonyms
    MGC82511 Peptide, RGS10 Peptide, 2310010N19Rik Peptide, regulator of G-protein signaling 10 Peptide, regulator of G-protein signaling 10 L homeolog Peptide, regulator of G protein signaling 10 Peptide, regulator of G-protein signalling 10 Peptide, RGS10 Peptide, rgs10.L Peptide, rgs10 Peptide, Rgs10 Peptide
    Background
    Regulator of G protein signaling (RGS) family members are regulatory molecules that act as GTPase activating proteins (GAPs) for G alpha subunits of heterotrimeric G proteins. RGS proteins are able to deactivate G protein subunits of the Gi alpha, Go alpha and Gq alpha subtypes. They drive G proteins into their inactive GDP-bound forms. Regulator of G protein signaling 10 belongs to this family. All RGS proteins share a conserved 120-amino acid sequence termed the RGS domain. This protein associates specifically with the activated forms of the two related G-protein subunits, G-alphai3 and G-alphaz but fails to interact with the structurally and functionally distinct G-alpha subunits. Regulator of G protein signaling 10 protein is localized in the nucleus. Two transcript variants encoding different isoforms have been found for this gene.

    Protein Interaction Partner: CALM1,GNAI1,GNAI3,GNAO1,GNAZ,GNRHR,PRKACA,ACP6,EIF6,GNAI1,GNAI3,GNAZ,SAP18

    Protein Size: 181
    Molecular Weight
    21 kDa
    Gene ID
    6001
    NCBI Accession
    NM_001005339, NP_001005339
    UniProt
    Q96GN0
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