Regulator of G-Protein Signaling 10 (RGS10) (N-Term) Peptide
RGS10
Reactivity: Mouse
Host: Synthetic
BP, FACS, WB
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- Target See all RGS10 products
- RGS10 (Regulator of G-Protein Signaling 10 (RGS10))
- Protein Region
- N-Term
- Origin
- Mouse
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Flow Cytometry (FACS), Western Blotting (WB)
- Sequence
- MFTRAVSRLS RKRPPSDIHD GDGSSSSGHQ SLKSTAKWAS SLENLLEDPE
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-Rgs10 Antibody(ARP42856_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- RGS10 (Regulator of G-Protein Signaling 10 (RGS10))
- Synonyms
- MGC82511 Peptide, RGS10 Peptide, 2310010N19Rik Peptide, regulator of G-protein signaling 10 Peptide, regulator of G-protein signaling 10 L homeolog Peptide, regulator of G protein signaling 10 Peptide, regulator of G-protein signalling 10 Peptide, RGS10 Peptide, rgs10.L Peptide, rgs10 Peptide, Rgs10 Peptide
- Background
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Rgs10 inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Rgs10 associates specifically with the activated forms of the G protein subunits G(i)-alpha and G(z)-alpha but fails to interact with the structurally and functionally distinct G(s)-alpha subunit. Activity of Rgs10 on G(z)-alpha is inhibited by palmitoylation of the G-protein.
Alias Symbols: 2310010N19Rik, MGC129414
Protein Size: 181 - Molecular Weight
- 21 kDa
- Gene ID
- 67865
- NCBI Accession
- NM_026418, NP_080694
- UniProt
- Q9CQE5
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