SIN3 Transcription Regulator Homolog B (SIN3B) (Middle Region) Peptide
SIN3B
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all SIN3B products
- SIN3B (SIN3 Transcription Regulator Homolog B (SIN3B))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-SIN3B antibody (Catalog #: ARP50590_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- SIN3B (SIN3 Transcription Regulator Homolog B (SIN3B))
- Synonyms
- fj63d08 Peptide, si:dkey-6n6.6 Peptide, wu:fj63d08 Peptide, 2810430C10Rik Peptide, SIN3 transcription regulator family member B Peptide, SIN3 transcription regulator family member B S homeolog Peptide, transcriptional regulator, SIN3B (yeast) Peptide, sin3b Peptide, SIN3B Peptide, sin3b.S Peptide, Sin3b Peptide
- Background
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SIN3B acts as a transcriptional repressor. It interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Also, it interacts with MAD-MAX heterodimers by binding to MAD. The heterodimer then represses transcription by tethering SIN3B to DNA. The gene is also able to form a complex with FOXK1 which represses transcription
Alias Symbols: KIAA0700
Protein Interaction Partner: HDAC1,HDAC9,IKZF1,IKZF4,MAD1L1,MXD1,MXI1,REST,SETDB1,ZBTB16,HCFC1,HDAC1,HDAC9,IKZF1,IKZF2,IKZF3,IKZF4,MECP2,RNF220,SAP30,SETDB1,SUDS3,WHSC1,ZBTB16
Protein Size: 1162 - Molecular Weight
- 133 kDa
- Gene ID
- 23309
- NCBI Accession
- NM_015260, NP_056075
- UniProt
- O75182
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