SIN3B Products
(SIN3 Transcription Regulator Homolog B (SIN3B))
Categories
Acts as a transcriptional repressor. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Interacts with MAD-MAX heterodimers by binding to MAD. The heterodimer then represses transcription by tethering SIN3B to DNA. Also forms a complex with FOXK1 which represses transcription (By similarity).
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Featured SIN3B Categories
SIN3B Antibodies
High quality antibodies with extensive validation data.
SIN3B Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended SIN3B Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IF, IHC, ICC
Validations
- (3)
Cat. No.
ABIN6265088
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IF, IHC
Validations
- (2)
Cat. No.
ABIN7162487
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat
Application
WB
Validations
- (1)
- (2)
Cat. No.
ABIN2784242
Quantity
100 μL
Datasheet
Datasheet
Recommended SIN3B Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1320021
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1320023
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
Cat. No.
ABIN3095414
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our SIN3B products
: "Integrative proteomics reveals an increase in non-degradative ubiquitylation in activated CD4+ T cells." in: Nature immunology, Vol. 20, Issue 6, pp. 747-755, (2019) (PubMed).: "Precision Electrophile Tagging in Caenorhabditis elegans." in: Biochemistry, Vol. 57, Issue 2, pp. 216-220, (2018) (PubMed).
: "Chromatin-Associated Protein SIN3B Prevents Prostate Cancer Progression by Inducing Senescence." in: Cancer research, Vol. 77, Issue 19, pp. 5339-5348, (2017) (PubMed).
: "Senescence-associated SIN3B promotes inflammation and pancreatic cancer progression." in: The Journal of clinical investigation, Vol. 124, Issue 5, pp. 2125-35, (2014) (PubMed).
: "The human SIN3B corepressor forms a nucleolar complex with leukemia-associated ETO homologues." in: BMC molecular biology, Vol. 9, pp. 8, (2008) (PubMed).
Synonyms and alternative names related to SIN3B
SIN3 transcription regulator family member B (sin3b), SIN3 transcription regulator family member B (SIN3B), SIN3 transcription regulator family member B S homeolog (sin3b.S), SIN3 transcription regulator family member B (Sin3b), transcriptional regulator, SIN3B (yeast) (Sin3b), 2810430C10Rik, fj63d08, si:dkey-6n6.6, wu:fj63d08Protein level used designations for SIN3B
- paired amphipathic helix protein Sin3b
- SIN3 homolog B, transcription regulator
- SIN3 homolog B, transcriptional regulator
- SIN3 transcription regulator homolog B
- histone deacetylase complex subunit Sin3b
- transcriptional corepressor Sin3b
- transcriptional regulator, SIN3B
- transcriptional regulator, SIN3 yeast homolog B
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