SMAD, Mothers Against DPP Homolog 6 (SMAD6) Peptide
SMAD6
Reactivity: Human, Drosophila melanogaster
Host: Synthetic
BP, WB
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- Target See all SMAD6 products
- SMAD6 (SMAD, Mothers Against DPP Homolog 6 (SMAD6))
- Origin
- Human, Drosophila melanogaster
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-SMAD6 antibody (Catalog #: P100717_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- SMAD6 (SMAD, Mothers Against DPP Homolog 6 (SMAD6))
- Synonyms
- madh6 Peptide, madh7 Peptide, Xsmad6 Peptide, hst17432 Peptide, AOVD2 Peptide, HsT17432 Peptide, MADH6 Peptide, MADH7 Peptide, Madh6 Peptide, b2b390Clo Peptide, Smad6-like Peptide, smad6 Peptide, wu:fb22g05 Peptide, SMAD family member 6 Peptide, SMAD family member 6a Peptide, smad6 Peptide, SMAD6 Peptide, Smad6 Peptide, smad6a Peptide
- Background
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SMAD6 (mothers against decapentaplegic homolog 6) is an antagonist of signaling by TGF-beta (transforming growth factor) type 1 receptor superfamily members, has been shown to inhibit selectively BMP (bone morphogenetic proteins) signaling by competing with the co-SMAD SMAD4 for receptor-activated SMAD1. SMAD6 is an inhibitory SMAD (I-SMAD) or antagonistic SMAD.
Alias Symbols: HsT17432, MADH6, MADH7
Protein Interaction Partner: BMPR1B,HOXC8,MAP3K7,RNF111,RUNX2,SMAD1,SMAD7,SMURF1,SMURF2,STAMBP,STRAP,TAB1,TGFBR1,TOB1,CTBP1,HOXC8,MAP3K7,PIAS4,RNF111,SMAD1,SMAD2,SMAD4,SMAD7,STAMBP,STRAP,TAB1,YAP1
Protein Size: 496 - Molecular Weight
- 53 kDa
- Gene ID
- 4091
- NCBI Accession
- NM_005585, NP_005576
- UniProt
- O43541
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