TERF1 Interacting Nuclear Factor 2 (TIN2) (Middle Region) Peptide
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- Target See all TINF2 (TIN2) products
- TINF2 (TIN2) (TERF1 Interacting Nuclear Factor 2 (TIN2))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-TINF2 antibody (Catalog #: ARP58338_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- TINF2 (TIN2) (TERF1 Interacting Nuclear Factor 2 (TIN2))
- Synonyms
- DKCA3 Peptide, TIN2 Peptide, AW552114 Peptide, D14Wsu146e Peptide, Tin2 Peptide, TERF1 interacting nuclear factor 2 Peptide, Terf1 (TRF1)-interacting nuclear factor 2 Peptide, TINF2 Peptide, Tinf2 Peptide
- Background
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TINF2 is a component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double-stranded TTAGGG repeats added by telomerase and protects chromosome ends, without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways. It plays a role in shelterin complex assembly.
Alias Symbols: TIN2, DKCA3
Protein Interaction Partner: ACD,TERF1,TERF2,ACD,TERF1,TERF2,ACD,POT1,TERF1,TERF2,TERF2IP
Protein Size: 451 - Molecular Weight
- 50 kDa
- Gene ID
- 26277
- NCBI Accession
- NM_001099274, NP_001092744
- UniProt
- Q9BSI4
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