anti-Mouse (Murine) Cyclin D1 antibody for Functional Studies

Recommended Cyclin D1 Antibody (supplied by: Log in to see )

Antigen
Cyclin D1 (CCND1) Antibodies
  • BCL1
  • D11S287E
  • PRAD1
  • U21B31
  • AI327039
  • CycD1
  • Cyl-1
  • bcl-1
  • cD1
  • cb161
  • cycd1
  • etID37810.7
  • fb52e01
  • fc45c08
  • fc83a12
  • id:ibd1198
  • wu:fb52e01
  • wu:fc45c08
  • wu:fc83a12
  • ccnd1b
  • prad1
  • ccnd1
  • ccnd1a
  • bcl1
  • d11s287e
  • u21b31
  • CCND1
  • cyclin D1
  • cyclin D1 S homeolog
  • cyclin D1 L homeolog
  • CCND1
  • Ccnd1
  • ccnd1
  • ccnd1.S
  • ccnd1.L
Epitope
AA 1-295
63
56
36
25
19
12
12
10
9
8
8
7
6
5
5
5
4
4
4
4
4
4
4
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Non-Human Primate, Rat (Rattus)
513
274
247
44
38
17
17
16
15
4
4
4
4
4
3
3
2
2
2
2
1
1
1
1
1
1
1
Host
Mouse
357
237
15
6
Clonality
Monoclonal
Conjugate
This Cyclin D1 antibody is conjugated to PE
31
27
16
13
9
7
7
4
4
4
4
4
4
4
4
4
4
4
4
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
Application
Flow Cytometry (FACS), Functional Studies (Func), Immunocytochemistry (ICC), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Western Blotting (WB)
537
197
157
149
142
122
99
77
46
44
22
8
7
5
3
3
1
1
Options
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Catalog No. ABIN4888512
$ 506.25
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
12.760485 ABIN4888511 FACS Func ICC IHC (f) IHC (p) IP WB Mouse IgG2a AA 1-295 Log in to see DCS-6 0
1 ABIN211137 Func ICC IP WB Rabbit IgG AA 285-295 Log in to see Polyclonal 0
1 ABIN386923 Func IF IP WB Rabbit IgG C-Term Log in to see Polyclonal 0
1 ABIN5862122 FACS Func IF/ICC IHC IP WB Mouse IgG2a AA 1-295 Log in to see 0
1 ABIN5862123 FACS Func IF/ICC IHC IP WB PE Mouse IgG2a AA 1-295 Log in to see 0

General

Antigen Cyclin D1 (CCND1) Antibodies
Epitope AA 1-295
(63), (56), (36), (25), (19), (12), (12), (10), (9), (8), (8), (7), (6), (5), (5), (5), (4), (4), (4), (4), (4), (4), (4), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Non-Human Primate, Rat (Rattus)
(513), (274), (247), (44), (38), (17), (17), (16), (15), (4), (4), (4), (4), (4), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Host Mouse
(357), (237), (15), (6)
Clonality (Clone)
Monoclonal   ( )
Conjugate This Cyclin D1 antibody is conjugated to PE
(31), (27), (16), (13), (9), (7), (7), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1)
Application Flow Cytometry (FACS), Functional Studies (Func), Immunocytochemistry (ICC), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Western Blotting (WB)
(537), (197), (157), (149), (142), (122), (99), (77), (46), (44), (22), (8), (7), (5), (3), (3), (1), (1)
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Product Details anti-Cyclin D1 Antibody

Target Details Cyclin D1 Application Details Handling Images
Specificity The mouse monoclonal antibody DCS-6 recognizes cyclin D1, an ubiquitously expressed 33 kDa protein that migrates as a 36 kDa band under reducing SDS-PAGE conditions.
Characteristics The purified antibody is conjugated with R-Phycoerythrin (PE) under optimum conditions. The conjugate is purified by size-exclusion chromatography.
Immunogen recombinant human cyclin D1 (amino acids 1-295)
Clone DCS-6
Isotype IgG2a
Plasmids, Primers & others

Target Details Cyclin D1

Product Details anti-Cyclin D1 Antibody Application Details Handling Images back to top
Antigen
Alternative Name Cyclin D1 (CCND1 Antibody Abstract)
Background Cyclin D1 (PRAD1, Bcl-1) is a cytoplasmic and nuclear protein, which is synthesized during G1 phase and assembles with either cyclin-dependent kinase 4 (CDK4) or CDK6 in response to growth factor stimulation. D-type cyclin-CDK complexes act to inactivate the growth-suppressive function of the Rb protein through its phosphorylation, and titrate CDK inhibitors such as p21Cip1 and p27Kip1. Whereas during G1 phase cyclin D1 accumulates in the nucleus, it translocates into the cytoplasm during S phase. Without growth factor-mediated stimulation cyclin D1 is unstable, and undergoes ubiquitin-mediated degradation, which is triggered by its phosphorylation. Cyclin D1 destabilization participates in G1/S phase arrest.
Pathways PI3K-Akt Signaling, Cell Division Cycle, Mitotic G1-G1/S Phases, ER-Nucleus Signaling

Application Details

Product Details anti-Cyclin D1 Antibody Target Details Cyclin D1 Handling Images back to top
Application Notes The reagent is designed for Flow Cytometry analysis.
Restrictions For Research Use only

Handling

Product Details anti-Cyclin D1 Antibody Target Details Cyclin D1 Application Details Images back to top
Storage 4 °C
Storage Comment Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light. Do not use after expiration date stamped on vial label.