anti-Yeast (Saccharomyces cerevisiae) PDPK1 antibody for Western Blotting
Recommended PDPK1 Antibody (supplied by: Log in to see )
- Antigen
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3-phosphoinositide Dependent Protein Kinase-1 (PDPK1) Antibodies
show synonyms for this antigen- pdpk1
- MGC82080
- PDK1
- PDPK2
- PRO0461
- Pdk1
- ATP5A
- si:zfos-979f1.3
- 1210
- BG02759
- CG1201
- CG1210
- DSTPK61
- Dmel\\CG1210
- Dstpk61
- PDK
- PDK-1
- PDK1/Pk61C
- PK61C
- Pk61C
- Pk61C/PDK1
- dPDK-1
- dPDK1
- dSTPK61
- pk61c
- 3'-phosphoinositide-dependent protein kinase 1
- 3-PHOSPHOINOSITIDE-DEPENDENT PROTEIN KINASE 1
- ATPDK1
- AtPDK1
- T32M21.110
- T32M21_110
- zgc:77318
- 3-phosphoinositide dependent protein kinase 1
- 3-phosphoinositide dependent protein kinase 1 L homeolog
- 3-phosphoinositide dependent protein kinase-1
- ATP synthase, H+ transporting, mitochondrial Fo complex subunit C2 (subunit 9)
- 3-phosphoinositide-dependent protein kinase 1
- pyruvate dehydrogenase kinase, isozyme 1
- pyruvate dehydrogenase kinase 1
- Phosphoinositide-dependent kinase 1
- 3'-phosphoinositide-dependent protein kinase 1
- 3-phosphoinositide dependent protein kinase 1b
- PDPK1
- pdpk1.L
- pdpk1
- Pdpk1
- ATP5G2
- LOC100380750
- pdk1
- PDK1
- Pdk1
- pdk-1
- pdpk1b
- Epitope
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Middle Region
Alternatives - Reactivity
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Cow (Bovine), Dog (Canine), Guinea Pig, Horse (Equine), Human, Mouse (Murine), Rabbit, Rat (Rattus), Yeast (Saccharomyces cerevisiae)
Alternatives - Host
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Rabbit
Alternatives - Clonality
- Conjugate
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This PDPK1 antibody is un-conjugated
Alternatives - Application
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Western Blotting (WB)
Alternatives - Options
- Supplier
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- Supplier Product No.
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Catalog No. ABIN2777432
$ 289.00
Plus shipping costs $45.00
Plus shipping costs $45.00
General |
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|---|---|
| Antigen | 3-phosphoinositide Dependent Protein Kinase-1 (PDPK1) Antibodies |
| Epitope | Middle Region Alternatives |
| Reactivity | Cow (Bovine), Dog (Canine), Guinea Pig, Horse (Equine), Human, Mouse (Murine), Rabbit, Rat (Rattus), Yeast (Saccharomyces cerevisiae) Alternatives |
| Host | Rabbit Alternatives |
| Clonality | |
| Conjugate | This PDPK1 antibody is un-conjugated Alternatives |
| Application |
Western Blotting (WB)
Alternatives
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|
1 reference available |
| Supplier | Log in to see |
Product Details anti-PDPK1 AntibodyTarget Details PDPK1 Application Details Handling References for anti-PDPK1 antibody (ABIN2777432) Images |
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| Blocking Peptide | Blocking peptide for this product available: ABIN981538 |
| Sequence | ATMEHHANRG VYPPIQVHVT LGNEDLTVKM SDRGGGVPLR KIDRLFNYMY |
| Predicted Reactivity | Cow: 86%, Dog: 79%, Guinea Pig: 86%, Horse: 86%, Human: 100%, Mouse: 86%, Rabbit: 86%, Rat: 86%, Yeast: 90% |
| Characteristics | This is a rabbit polyclonal antibody against PDK1. It was validated on Western Blot using a cell lysate as a positive control. |
| Purification | Affinity Purified |
| Immunogen | The immunogen is a synthetic peptide directed towards the middle region of human PDK1 |
| Plasmids, Primers & others | |
Target Details PDPK1Product Details anti-PDPK1 Antibody Application Details Handling References for anti-PDPK1 antibody (ABIN2777432) Images back to top |
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| Antigen | |
| Alternative Name | PDK1 (PDPK1 Antibody Abstract) |
| Background |
Pyruvate dehydrogenase (PDH) is a mitochondrial multienzyme complex that catalyzes the oxidative decarboxylation of pyruvate and is one of the major enzymes responsible for the regulation of homeostasis of carbohydrate fuels in mammals. The enzymatic activity is regulated by a phosphorylation/dephosphorylation cycle. Phosphorylation of PDH by a specific pyruvate dehydrogenase kinase (PDK) results in inactivation.Pyruvate dehydrogenase (PDH) is a mitochondrial multienzyme complex that catalyzes the oxidative decarboxylation of pyruvate and is one of the major enzymes responsible for the regulation of homeostasis of carbohydrate fuels in mammals. The enzymatic activity is regulated by a phosphorylation/dephosphorylation cycle. Phosphorylation of PDH by a specific pyruvate dehydrogenase kinase (PDK) results in inactivation. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. Alias Symbols: - Protein Interaction Partner: EGFR, PDK1, KAT2B, USP4, UBC, MYC, XRCC6, SGK1, DLAT, RPS6KB1, PDK2, PDHA1, YWHAQ, RPTOR, RALGDS, PKN2, PKN1, MTOR, AKT1, Protein Size: 436 |
| Molecular Weight | 47 kDa |
| Gene ID | 5163 |
| NCBI Accession | NM_002610, NP_002601 |
| UniProt | Q15118 |
| Pathways | PI3K-Akt Signaling, TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cell-Cell Junction Organization, Regulation of Cell Size, Skeletal Muscle Fiber Development, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, VEGFR1 Specific Signals |
Application DetailsProduct Details anti-PDPK1 Antibody Target Details PDPK1 Handling References for anti-PDPK1 antibody (ABIN2777432) Images back to top |
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| Application Notes | Optimal working dilutions should be determined experimentally by the investigator. |
| Comment |
Antigen size: 436 AA |
| Restrictions | For Research Use only |
HandlingProduct Details anti-PDPK1 Antibody Target Details PDPK1 Application Details References for anti-PDPK1 antibody (ABIN2777432) Images back to top |
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| Format | Liquid |
| Concentration | Lot specific |
| Buffer | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose. |
| Preservative | Sodium azide |
| Precaution of Use | This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only. |
| Handling Advice | Avoid repeated freeze-thaw cycles. |
| Storage | -20 °C |
| Storage Comment | For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles. |
References for anti-PDPK1 antibody (ABIN2777432)Product Details anti-PDPK1 Antibody Target Details PDPK1 Application Details Handling Images back to top |
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| Background publications |
Ohba, Watanabe, Murakami, Radovanovic, Iino, Ishida, Tosa, Ono, Ito: "Amlodipine inhibits cell proliferation via PKD1-related pathway." in: Biochemical and biophysical research communications, Vol. 369, Issue 2, pp. 376-81, 2008 |
ImagesProduct Details anti-PDPK1 Antibody Target Details PDPK1 Application Details Handling References for anti-PDPK1 antibody (ABIN2777432) back to top |
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| Supplier Images |
Host: Rabbit Target Name: CHAD Sample Type: Human Adult Placenta Antibody Dilution: 1...
Host: Rabbit Target Name: PDK1 Sample Tissue: Mouse Testis Antibody Dilution: 1ug/ml
Host: Rabbit Target Name: PDK2 Sample Type: Human Jurkat Antibody Dilution: 1.0ug/ml ...
WB Suggested Anti-PDK1 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:1562500 Positiv...
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