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|Antigen||Protein Phosphatase 2, Regulatory Subunit B, beta (PPP2R2B) Antibodies|
|Epitope||AA 110-139 Alternatives|
|Conjugate||This PPP2R2B antibody is un-conjugated Alternatives|
Enzyme Immunoassay (EIA), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
|3 references available|
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Product Details anti-PPP2R2B AntibodyTarget Details PPP2R2B Application Details Handling References for anti-PPP2R2B antibody (ABIN453788) Images
|Specificity||This antibody recognizes PPP2R2B.|
|Cross-Reactivity (Details)||Species reactivity (tested):Human.|
|Purification||Protein A Chromatography followed by peptide Affinity purification.|
|Immunogen||KLH conjugated synthetic peptide between 110~139 amino acids from the Center region of Human PPP2R2B. Genename: PPP2R2B|
Target Details PPP2R2BProduct Details anti-PPP2R2B Antibody Application Details Handling References for anti-PPP2R2B antibody (ABIN453788) Images back to top
|Alternative Name||PPP2R2B (PPP2R2B Antibody Abstract)|
|Background||PPP2R2B belongs to the phosphatase 2 regulatory subunit B family. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This protein is a beta isoform of the regulatory subunit B55 subfamily.Synonyms: B55-beta isoform, PP2A subunit B B-beta isoform, PR55-beta isoform, R2-beta isoform, Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform, protein phosphatase 2A 55 kDa regulatory subunit B beta|
|Molecular Weight||51710 Da|
|Pathways||PI3K-Akt Signaling, Mitotic G1-G1/S Phases, Hepatitis C|
Application DetailsProduct Details anti-PPP2R2B Antibody Target Details PPP2R2B Handling References for anti-PPP2R2B antibody (ABIN453788) Images back to top
ELISA: 1/1,000. Western blotting: 1/100-1/500. Immunohistochemistry: 1/50-1/100. Immunofluorescence: 1/10-1/50. Flow Cytometry: 1/10-1/50.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
|Restrictions||For Research Use only|
HandlingProduct Details anti-PPP2R2B Antibody Target Details PPP2R2B Application Details References for anti-PPP2R2B antibody (ABIN453788) Images back to top
|Buffer||PBS with 0.09 % (W/V) Sodium Azide as preservative.|
|Precaution of Use||This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
|Handling Advice||Avoid repeated freezing and thawing.|
|Storage||4 °C/-20 °C|
|Storage Comment||Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.|
References for anti-PPP2R2B antibody (ABIN453788)Product Details anti-PPP2R2B Antibody Target Details PPP2R2B Application Details Handling Images back to top
Rajkiewicz, Sułek-Piatkowska, Krysa, Zdzienicka, Szirkowiec, Zaremba: "Screening for premutation in the FMR1 gene in male patients suspected of spinocerebellar ataxia." in: Neurologia i neurochirurgia polska, Vol. 42, Issue 6, pp. 497-504, 2009
Ben-Israel, Sharf, Rechavi, Kleinberger: "Adenovirus E4orf4 protein downregulates MYC expression through interaction with the PP2A-B55 subunit." in: Journal of virology, Vol. 82, Issue 19, pp. 9381-8, 2008
Strack, Zaucha, Ebner, Colbran, Wadzinski: "Brain protein phosphatase 2A: developmental regulation and distinct cellular and subcellular localization by B subunits." in: The Journal of comparative neurology, Vol. 392, Issue 4, pp. 515-27, 1998
ImagesProduct Details anti-PPP2R2B Antibody Target Details PPP2R2B Application Details Handling References for anti-PPP2R2B antibody (ABIN453788) back to top