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IL12A Protein (AA 23-219) (His tag)

IL12A Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % WB, Ct
Catalog No. ABIN1000979
  • Target See all IL12A Proteins
    IL12A (Interleukin 12 alpha (IL12A))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 23-219
    Origin
    • 7
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Source
    • 15
    • 12
    • 4
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This IL12A protein is labelled with His tag.
    Application
    Western Blotting (WB), Control (Ct)
    Purpose
    Interleukin-12p35 (IL-12p35) (Western Blot Control)
    Sequence
    RNLPVATPDP GMFPCLHHSQ NLLRAVSNML QKARQTLEFY RNLPVATPDP GMFPCLHHSQ NLLRAVSNML QKARQTLEFY RNLPVATPDP GMFPCLHHSQ NLLRAVSNML QKARQTLEFY RNLPVATPDP GMFPCLHHSQ NLLRAVSNML QKARQTLEFY LEEPDFYKTK IKLCILLHAF RIRAVTIDRV MSYLNAS
    Characteristics
    recombinant Interleukin-12p35 comprises a 197 amino acid fragment (23-219) corresponding to the mature Interleukin-12p35 chain protein and is expressed in E. coli with an amino-terminal hexahistidine tag.
    Purity
    > 95 %
    Top Product
    Discover our top product IL12A Protein
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Supplied in 1x Laemmli Buffer (25 mM Tris-HCl pH 6.8, 50 mM DTT, 1 % (w/v) SDS, 0.1 % (w/v) Bromophenol Blue, 2.5 % Glycerol).
    Preservative
    Dithiothreitol (DTT)
    Precaution of Use
    This product contains Dithiothreitol (DTT): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C
  • Target
    IL12A (Interleukin 12 alpha (IL12A))
    Alternative Name
    Interleukin-12 p35 (IL12A Products)
    Synonyms
    CLMF Protein, IL-12A Protein, NFSK Protein, NKSF1 Protein, P35 Protein, CLMF2 Protein, IL-12B Protein, NKSF Protein, NKSF2 Protein, p40 Protein, Il-12b Protein, Il12p40 Protein, Il-12p40 Protein, Il12 Protein, IL-12p40 Protein, IL-12p35 Protein, Il-12a Protein, Ll12a Protein, p35 Protein, IL12p35 Protein, Il-12 p35 Protein, IL12p40 Protein, IL12 Protein, IL-12 p35 Protein, interleukin 12A Protein, interleukin 12B Protein, interleukin 12b Protein, interleukin 12a Protein, Interleukin 12 level Protein, IL12A Protein, IL12B Protein, Il12b Protein, Il12a Protein, IL12 Protein, il12a Protein
    Background
    Active IL-12 is a p70 disulphide-linked dimer composed of p35 and p40 subunits. The protein is a pleiotropic cytokine produced primarily by antigen presenting cells and has multiple effects on T lymphocytes and natural killer cells in terms of stimulating cytotoxicity, proliferation, production of other cytokines and Th1 subset differentiation.,IL-12A, Cytotoxic Lymphocyte Maturation Factor, CLMF, Natural Killer Cell Stimulation Factor 1, NKSF1, NFSK, subunit p35.
    Molecular Weight
    27.04 kDa
    UniProt
    P29459
    Pathways
    JAK-STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation
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