RPA3 Protein (AA 1-119, partial) (His tag)

Catalog No. ABIN1047599

Product Details

Target: RPA3 (Replication Protein A3, 14kDa (RPA3))

Protein Type: Recombinant

Protein Characteristics: AA 1-119, partial

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This RPA3 protein is labelled with His tag.

Application: SDS-PAGE (SDS), ELISA

Sequence: MVDMMDLPRS RINAGMLAQF IDKPVCFVGR LEKIHPTGKM FILSDGEGKN GTIELMEPLD EEISGIVEVV GRVTAKATIL CTSYVQFKED SHPFDLGLYN EAVKIIHDFP QFYPLGIVQ

Specificity: N-terminal 6xHis-tagged

Characteristics: Required for DNA recombination, repair and replication. The activity of RP-A is mediated by single-stranded DNA binding and protein interactions. Ref.7 Ref.9 Functions as component of the alternative replication protein A complex (aRPA). aRPA binds single-stranded DNA and probably plays a role in DNA repair, it does not support chromosomal DNA replication and cell cycle progression through S-phase. In vitro, aRPA cannot promote efficient priming by DNA polymerase alpha but supports DNA polymerase delta synthesis in the presence of PCNA and replication factor C (RFC), the dual incision/excision reaction of nucleotide excision repair and RAD51-dependent strand exchange. Ref.7 Ref.9

Purity: 95 %

Application Details

Comment:

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Restrictions: For Research Use only

Handling

Format: Lyophilized or Liquid

Buffer: Liquid protein in buffer: 10 mM Tris-HCl, 1 mM EDTA, pH 8.0,50% glycerol

Storage: -20 °C

Target Details

Target: RPA3 (Replication Protein A3, 14kDa (RPA3))

Alternative Name: Replication protein A 14 kDa subunit (RPA3 Products)

Synonyms: REPA3 Protein, 14kDa Protein, C330026P08Rik Protein, im:6908405 Protein, zgc:56310 Protein, zgc:86697 Protein, rpa3 Protein, MGC82610 Protein, RPA3 Protein, repa3 Protein, replication protein A3 Protein, replication protein A3 S homeolog Protein, replication protein A3 L homeolog Protein, RPA3 Protein, Rpa3 Protein, rpa3 Protein, rpa3.S Protein, rpa3.L Protein

Background: Synonyms: Replication factor A protein 3

Molecular Weight: 17.4 kD

UniProt: P35244

Pathways: Telomere Maintenance, DNA Damage Repair, Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA