RPA3 Protein (AA 1-119, partial) (His tag)
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- Target See all RPA3 Proteins
- RPA3 (Replication Protein A3, 14kDa (RPA3))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-119, partial
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This RPA3 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS), ELISA
- Sequence
- MVDMMDLPRS RINAGMLAQF IDKPVCFVGR LEKIHPTGKM FILSDGEGKN GTIELMEPLD EEISGIVEVV GRVTAKATIL CTSYVQFKED SHPFDLGLYN EAVKIIHDFP QFYPLGIVQ
- Specificity
- N-terminal 6xHis-tagged
- Characteristics
- Required for DNA recombination, repair and replication. The activity of RP-A is mediated by single-stranded DNA binding and protein interactions. Ref.7 Ref.9 Functions as component of the alternative replication protein A complex (aRPA). aRPA binds single-stranded DNA and probably plays a role in DNA repair, it does not support chromosomal DNA replication and cell cycle progression through S-phase. In vitro, aRPA cannot promote efficient priming by DNA polymerase alpha but supports DNA polymerase delta synthesis in the presence of PCNA and replication factor C (RFC), the dual incision/excision reaction of nucleotide excision repair and RAD51-dependent strand exchange. Ref.7 Ref.9
- Purity
- 95 %
- Top Product
- Discover our top product RPA3 Protein
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- Comment
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Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
- Restrictions
- For Research Use only
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- Format
- Lyophilized or Liquid
- Buffer
- Liquid protein in buffer: 10 mM Tris-HCl, 1 mM EDTA, pH 8.0,50% glycerol
- Storage
- -20 °C
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- Target
- RPA3 (Replication Protein A3, 14kDa (RPA3))
- Alternative Name
- Replication protein A 14 kDa subunit (RPA3 Products)
- Synonyms
- REPA3 Protein, 14kDa Protein, C330026P08Rik Protein, im:6908405 Protein, zgc:56310 Protein, zgc:86697 Protein, rpa3 Protein, MGC82610 Protein, RPA3 Protein, repa3 Protein, replication protein A3 Protein, replication protein A3 S homeolog Protein, replication protein A3 L homeolog Protein, RPA3 Protein, Rpa3 Protein, rpa3 Protein, rpa3.S Protein, rpa3.L Protein
- Background
- Synonyms: Replication factor A protein 3
- Molecular Weight
- 17.4 kD
- UniProt
- P35244
- Pathways
- Telomere Maintenance, DNA Damage Repair, Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA
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