BAG2 Protein (AA 1-211) (His tag)
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- Target See all BAG2 Proteins
- BAG2 (BCL2-Associated Athanogene 2 (BAG2))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-211
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This BAG2 protein is labelled with His tag.
- Purpose
- Recombinant Human Bcl-2-Associated Athanogene 1/BAG2 (N-6His)
- Sequence
- MGSSHHHHHH SSGLVPRGSH MAQAKINAKA NEGRFCRSSS MADRSSRLLE SLDQLELRVE ALREAATAVE QEKEILLEMI HSIQNSQDMR QISDGEREEL NLTANRLMGR TLTVEVSVET IRNPQQQESL KHATRIIDEV VNKFLDDLGN AKSHLMSLYS ACSSEVPHGP VDQKFQSIVI GCALEDQKKI KRRLETLLRN IENSDKAIKL LEHSKGAGSK TLQQNAESRF N
- Characteristics
- Recombinant Human BAG Family Molecular Chaperone Regulator 2/BAG2 is produced by our E. coli expression system. The target protein is expressed with sequence (Met1-Asn211) of Human BAG2 fused with a 6His tag at the N-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Sterility
- 0.2 μm filtered
- Endotoxin Level
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product BAG2 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - Buffer
- Lyophilized from a 0.2 μm filtered solution of 20 mM TrisHCl, 150 mM NaCl, pH 8.0.
- Handling Advice
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- Storage
- 4 °C/-20 °C/-80 °C
- Storage Comment
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Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months. - Expiry Date
- 3 months
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- Target
- BAG2 (BCL2-Associated Athanogene 2 (BAG2))
- Alternative Name
- BAG2 (BAG2 Products)
- Synonyms
- bag2 Protein, MGC89300 Protein, BAG2 Protein, ATBAG2 Protein, BCL-2-associated athanogene 2 Protein, MTG10.13 Protein, MTG10_13 Protein, BAG-2 Protein, dJ417I1.2 Protein, zgc:64195 Protein, 2610042A13Rik Protein, BC016230 Protein, BCL2 associated athanogene 2 Protein, BCL-2-associated athanogene 2 Protein, BCL2-associated athanogene 2 Protein, Bcl2-associated athanogene 2 Protein, bag2 Protein, BAG2 Protein, Bag2 Protein
- Sub Type
- Fusionprotein
- Background
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BAG Family Molecular Chaperone Regulator 2 (BAG2) is a member of the Bag family whose members compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. BAG2 contains 1 BAG domain and is a important component of the HSC 70/CHIP chaperone-dependent ubiquitin ligase complex. In mammalian cells BAG1, BAG2, and BAG3 bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner.
Alternative Names: BAG Family Molecular Chaperone Regulator 2, BAG-2, Bcl-2-Associated Athanogene 2, BAG2 - Molecular Weight
- 25.9 kDa
- UniProt
- O95816
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