Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

HEPACAM Protein (AA 34-240) (His tag)

HEPACAM Origin: Human Host: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN1096816
  • Target See all HEPACAM Proteins
    HEPACAM (Hepatic and Glial Cell Adhesion Molecule (HEPACAM))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 34-240
    Origin
    • 2
    • 1
    Human
    Source
    • 1
    • 1
    • 1
    Human Cells
    Purification tag / Conjugate
    This HEPACAM protein is labelled with His tag.
    Purpose
    Recombinant Human Hepatocyte Cell Adhesion Molecule/HepaCAM (C-6His)
    Sequence
    VNITSPVRLI HGTVGKSALL SVQYSSTSSD RPVVKWQLKR DKPVTVVQSI GTEVIGTLRP DYRDRIRLFE NGSLLLSDLQ LADEGTYEVE ISITDDTFTG EKTINLTVDV PISRPQVLVA STTVLELSEA FTLNCSHENG TKPSYTWLKD GKPLLNDSRM LLSPDQKVLT ITRVLMEDDD LYSCMVENPI SQGRSLPVKI TVYRRSSVDH HHHHH
    Characteristics
    Recombinant Human Hepatocyte Cell Adhesion Molecule/HEPACAM produced by transfected human cellss is a secreted protein with sequence (Val34-Ser240) of Human HEPACAM fused with a polyhistidine tag at the C-terminus.
    Purity
    > 95 % as determined by reducing SDS-PAGE.
    Sterility
    0.2 μm filtered
    Endotoxin Level
    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    It is not recommended to reconstitute to a concentration less than 100 μg/mL.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.
    Handling Advice
    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    Storage
    4 °C/-20 °C/-80 °C
    Storage Comment
    Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
    Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
    Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    Expiry Date
    3 months
  • Target
    HEPACAM (Hepatic and Glial Cell Adhesion Molecule (HEPACAM))
    Alternative Name
    hepacam (HEPACAM Products)
    Synonyms
    GlialCAM Protein, MLC2A Protein, MLC2B Protein, 2900042E01Rik Protein, Hepn1 Protein, hepatic and glial cell adhesion molecule Protein, hepatocyte cell adhesion molecule Protein, HEPACAM Protein, Hepacam Protein
    Sub Type
    Fusionprotein
    Background
    Hepatocyte Cell Adhesion Molecule (HEPACAM) is a single-pass type I membrane protein that localizes to the cytoplasmic side of the cell membrane. HEPACAM includes a signal sequence (amino acid 1-33), an extracellular region (amino acid 34-240) with one Ig-like C2-type domain and one Ig-like V-type domain, a transmembrane segment (amino acid 241-261), and a cytoplasmic domain (amino acid 262 - 416). The cytoplasmic domain plays an important role in regulation of cell-matrix adhesion and cell motility. HEPACAM acts as a homodimer and dimer formation occurs predominantly through cis interactions on the cell surface. HEPACAM is involved in cell motility and cell-matrix interactions. The expression of this gene is down-regulated or undetectable in many cancer cell lines, so this may be a tumor suppressor gene.
    Alternative Names: Hepatocyte Cell Adhesion Molecule, Protein HepaCAM, HEPACAM
    Molecular Weight
    24.09 kDa
    UniProt
    Q14CZ8
You are here:
Support