HEPACAM Protein (His tag)
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- Target See all HEPACAM Proteins
- HEPACAM (Hepatic and Glial Cell Adhesion Molecule (HEPACAM))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Human Cells
- Purification tag / Conjugate
- This HEPACAM protein is labelled with His tag.
- Purpose
- Recombinant Human HEPACAM Protein (His Tag)
- Sequence
- Val34-Ser240
- Characteristics
- Recombinant Human Hepatocyte Cell Adhesion Molecule is produced by our Mammalian expression system and the target gene encoding Val34-Ser240 is expressed with a 6His tag at the C-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product HEPACAM Protein
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Hepatic and Glial Cell Adhesion Molecule (HEPACAM) protein (Myc-DYKDDDDK Tag)
HEPACAM Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- HEPACAM (Hepatic and Glial Cell Adhesion Molecule (HEPACAM))
- Alternative Name
- HEPACAM (HEPACAM Products)
- Synonyms
- GlialCAM Protein, MLC2A Protein, MLC2B Protein, 2900042E01Rik Protein, Hepn1 Protein, hepatic and glial cell adhesion molecule Protein, hepatocyte cell adhesion molecule Protein, HEPACAM Protein, Hepacam Protein
- Background
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Background: Hepatocyte Cell Adhesion Molecule (HEPACAM) is a single-pass type I membrane protein that localizes to the cytoplasmic side of the cell membrane. HEPACAM includes a signal sequence (amino acid 1-33), an extracellular region (amino acid 34-240) with one Ig-like C2-type domain and one Ig-like V-type domain, a transmembrane segment (amino acid 241-261), and a cytoplasmic domain (amino acid 262 - 416). The cytoplasmic domain plays an important role in regulation of cell-matrix adhesion and cell motility. HEPACAM acts as a homodimer and dimer formation occurs predominantly through cis interactions on the cell surface. HEPACAM is involved in cell motility and cell-matrix interactions. The expression of this gene is down-regulated or undetectable in many cancer cell lines, so this may be a tumor suppressor gene.
Synonym: Hepatocyte Cell Adhesion Molecule, Protein HepaCAM, HEPACAM
- Molecular Weight
- 24.1 kDa
- UniProt
- Q14CZ8
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