CADM3 Protein (AA 25-330) (His tag)

Catalog No. ABIN1096873

Product Details

Target: CADM3 (Cell Adhesion Molecule 3 (CADM3))

Protein Type: Recombinant

Protein Characteristics: AA 25-330

Origin: Human

Source: Human Cells

Purification tag / Conjugate: This CADM3 protein is labelled with His tag.

Purpose: Recombinant Human Cell Adhesion Molecule 3/CADM3/IGSF4B/SynCAM3 (C-6His)

Sequence: NLSQDDSQPW TSDETVVAGG TVVLKCQVKD HEDSSLQWSN PAQQTLYFGE KRALRDNRIQ LVTSTPHELS ISISNVALAD EGEYTCSIFT MPVRTAKSLV TVLGIPQKPI ITGYKSSLRE KDTATLNCQS SGSKPAARLT WRKGDQELHG EPTRIQEDPN GKTFTVSSSV TFQVTREDDG ASIVCSVNHE SLKGADRSTS QRIEVLYTPT AMIRPDPPHP REGQKLLLHC EGRGNPVPQQ YLWEKEGSVP PLKMTQESAL IFPFLNKSDS GTYGCTATSN MGSYKAYYTL NVNDPSPVPS SSSTYHVDHH HHHH

Characteristics: Recombinant Human Cell Adhesion Molecule 3/CADM3 is produced with our mammalian expression system in human cells. The target protein is expressed with sequence (Asn25-His330) of Human CADM3 fused with a polyhistidine tag at the C-terminus.

Purity: > 95 % as determined by reducing SDS-PAGE.

Sterility: 0.2 μm filtered

Endotoxin Level: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.

Handling Advice: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Storage: 4 °C/-20 °C/-80 °C

Storage Comment: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Expiry Date: 3 months

Target Details

Target: CADM3 (Cell Adhesion Molecule 3 (CADM3))

Alternative Name: syncam3 (CADM3 Products)

Synonyms: BIgR Protein, IGSF4B Protein, NECL1 Protein, Necl-1 Protein, TSLL1 Protein, synCAM3 Protein, Igsf4b Protein, Necl1 Protein, SynCAM3 Protein, Tsll1 Protein, necl1 Protein, cell adhesion molecule 3 Protein, cell adhesion molecule 3 S homeolog Protein, CADM3 Protein, Cadm3 Protein, cadm3.S Protein

Sub Type: Fusionprotein

Background: Cell Adhesion Molecular Proteins are proteins located on the cell surface involved with the binding with other cells or with the extracellular matrix in the cell adhesion process. These proteins consists of three domains, an transmembrane domain, an intracellular domain that interacts with the cytoskeleton, and an extracellular domain that interacts with other CAMs of the same kind or with other CAMs or the extracellular matrix. Cell Adhesion Molecular 3 (CADM3) is a neural tissue-specific member of the nectin-like family of immunoglobulin superfamily. CADM3 interacts with EPB41L1 may regulate structure or function of cell-cell junctions. CADM3 has both calcium-independent homophilic cell-cell adhesion activity and calcium-independent heterophilic cell-cell adhesion activity with IGSF4, PVRL1 and PVRL3.
Alternative Names: Cell Adhesion Molecule 3, Brain Immunoglobulin Receptor, Immunoglobulin Superfamily Member 4B, IgSF4B, Nectin-Like Protein 1, NECL-1, Synaptic Cell Adhesion Molecule 3, SynCAM3, TSLC1-Like Protein 1, TSLL1, CADM3, IGSF4B, NECL1, SYNCAM3, TSLL1

Molecular Weight: 34.68 kDa

UniProt: Q8N126

Pathways: Cell-Cell Junction Organization