SENP8 Protein (AA 1-212) (His tag)
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- Target See all SENP8 Proteins
- SENP8 (SUMO/sentrin Specific Peptidase Family Member 8 (SENP8))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-212
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This SENP8 protein is labelled with His tag.
- Purpose
- Recombinant Human Sentrin-Specific Protease 8/SENP8 (N-6His)
- Sequence
- MGSSHHHHHH SSGLVPRGSH MDPVVLSYMD SLLRQSDVSL LDPPSWLNDH IIGFAFEYFA NSQFHDCSDH VSFISPEVTQ FIKCTSNPAE IAMFLEPLDL PNKRVVFLAI NDNSNQAAGG THWSLLVYLQ DKNSFFHYDS HSRSNSVHAK QVAEKLEAFL GRKGDKLAFV EEKAPAQQNS YDCGMYVICN TEALCQNFFR QQTESLLQLL TPAYITKKRG EWKDLIATLA KK
- Characteristics
- Recombinant Human Sentrin-Specific Protease 8/SENP8 is produced by our E. coli expression system. The target protein is expressed with sequence (Met1-Lys212) of Human SENP8.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Sterility
- 0.2 μm filtered
- Endotoxin Level
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product SENP8 Protein
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Reconstitution
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.
- Handling Advice
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- Storage
- -80 °C
- Storage Comment
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Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles. - Expiry Date
- 6 months
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- Target
- SENP8 (SUMO/sentrin Specific Peptidase Family Member 8 (SENP8))
- Alternative Name
- Sentrin-Specific Protease 8/SENP8 (SENP8 Products)
- Synonyms
- den1 Protein, nedp1 Protein, prsc2 Protein, MGC84956 Protein, F15L12.8 Protein, F15L12_8 Protein, 9130010J17Rik Protein, AU020827 Protein, Den1 Protein, Nedp1 Protein, Prsc2 Protein, DEN1 Protein, NEDP1 Protein, PRSC2 Protein, SUMO/sentrin peptidase family member, NEDD8 specific L homeolog Protein, Cysteine proteinases superfamily protein Protein, SUMO/sentrin specific peptidase 8 Protein, SUMO/sentrin peptidase family member, NEDD8 specific Protein, senp8.L Protein, AT5G60190 Protein, Senp8 Protein, SENP8 Protein
- Background
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Sentrin-Specific Protease 8 (SENP8) mediates the reversible covalent modification of proteins by NEDD8. SENP8 catalyzes the full-length NEDD8 to generate its mature form and deconjugation of NEDD8 from targeted proteins such as CUL2 , CUL4A in vivo, or p53. but it does not show activity against ubiquitin or SUMO proteins.
Alternative Names: Sentrin-Specific Protease 8, Deneddylase-1, NEDD8-Specific Protease 1, Protease Cysteine 2, Sentrin/SUMO-Specific Protease SENP8, SENP8, DEN1, NEDP1, PRSC2 - Molecular Weight
- 26.24 kDa
- UniProt
- Q96LD8
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