HPGDS Protein (His tag)
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- Target See all HPGDS Proteins
- HPGDS (Hematopoietic Prostaglandin D Synthase (HPGDS))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This HPGDS protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Purification
- purified by chromatography
- Purity
- > 95 % by SDS - PAGE
- Top Product
- Discover our top product HPGDS Protein
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- Comment
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Synonyms: Hematopoietic prostaglandin D synthase, GSTS, PGDS
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/ml (determined by Bradford assay)
- Buffer
- 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 0.15 M NaCl,1 MM DTT
- Storage
- 4 °C
- Storage Comment
- Avoid repeated freezing and thawing cycles.
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- Target
- HPGDS (Hematopoietic Prostaglandin D Synthase (HPGDS))
- Alternative Name
- HPGDS (HPGDS Products)
- Synonyms
- GSTS Protein, GSTS1-1 Protein, PGD2 Protein, PGDS Protein, L-PGDS Protein, LPGDS Protein, PDS Protein, PGDS2 Protein, XlGSTS1 Protein, gsts Protein, pgds Protein, H-PGDS Protein, Ptgds2 Protein, hpgds Protein, hpgds-a Protein, hpgds-b Protein, hpgdsa Protein, hematopoietic prostaglandin D synthase Protein, prostaglandin D2 synthase Protein, hematopoietic prostaglandin D synthase L homeolog Protein, HPGDS Protein, PTGDS Protein, hpgds Protein, Hpgds Protein, hpgds.L Protein
- Background
- HPGDS, also known as GSTS, is a sigma class glutathione-S-transferase family member. The enzyme catalyzes the conversion of PGH2 to PGD2 and plays a role in the production of prostanoids in the immune system and mast cells. The presence of this enzyme can be used to identify the differentiation stage of human megakaryocytes. Recombinant human HPGDS protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
- Molecular Weight
- 25.9 kDa (223aa), confirmed by MALDI-TOF
- NCBI Accession
- NP_055300
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