CBX3 Protein (His tag)
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- Target See all CBX3 Proteins
- CBX3 (Chromobox Homolog 3 (CBX3))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This CBX3 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Purification
- purified by using conventional chromatography.
- Purity
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product CBX3 Protein
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- Comment
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Synonyms: Chromobox protein homolog 3, HECH, HP1-GAMMA, HP1Hs-gamma
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/ml (determined by Bradford assay)
- Buffer
- 20 mM Tris-HCl buffer (pH 8.0) containing 20% glycerol, 0.1 M NaCl, 1 MM DTT
- Storage
- 4 °C
- Storage Comment
- Avoid repeated freezing and thawing cycles.
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- Target
- CBX3 (Chromobox Homolog 3 (CBX3))
- Alternative Name
- CBX3 (CBX3 Products)
- Synonyms
- HECH Protein, HP1-GAMMA Protein, HP1Hs-gamma Protein, Hp1-gamma Protein, HP1g Protein, M32 Protein, cbx3 Protein, cbx3a Protein, xhp1g Protein, wu:fb61b02 Protein, zgc:153397 Protein, chromobox 3 Protein, chromobox 3 L homeolog Protein, chromobox protein homolog 3 pseudogene Protein, chromobox homolog 3a (HP1 gamma homolog, Drosophila) Protein, CBX3 Protein, Cbx3 Protein, cbx3.L Protein, LOC100355282 Protein, cbx3a Protein
- Background
- CBX3, also known as chromobox protein homolog 3, seems to be involved in transcriptional silencing in heterochromatin-like complexes. This protein recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. It involved in the formation of functional kinetochore through interaction with MIS12 complex proteins. Recombinant human CBX3 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.
- Molecular Weight
- 23.4 kDa (207aa), confirmed by MALDI-TOF
- NCBI Accession
- NP_057671
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